Brain endothelial cell‐targeted gene therapy of neurovascular disorders

Abstract Neurovascular disorders are difficult to treat due to the blood–brain barrier (BBB), which prevents delivery of most drugs from the blood into the brain. Gene therapy can potentially overcome this barrier, but classical vectors are neither efficient nor specific enough to provide long‐lasti...

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Bibliographic Details
Main Authors: Serena Marchiò, Richard L Sidman, Wadih Arap, Renata Pasqualini
Format: Article
Language:English
Published: Springer Nature 2016-05-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201606407
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