Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity
Mannich bases functional groups were used, which is considered an inventive phenol formaldehyde resin was created in this study. The project was divided into two phases. The first portion involves creating a monomer of Mannich bases through a condensation reaction. The reaction occurs between aroma...
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University of Baghdad, College of Science for Women
2024-12-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8774 |
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| author | Tamador Ali Mahmood |
| author_facet | Tamador Ali Mahmood |
| author_sort | Tamador Ali Mahmood |
| collection | DOAJ |
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Mannich bases functional groups were used, which is considered an inventive phenol formaldehyde resin was created in this study. The project was divided into two phases. The first portion involves creating a monomer of Mannich bases through a condensation reaction. The reaction occurs between aromatic aldehyde (P-hydroxy benzaldehyde) and primary amines like (Metoclopramide, trimethoprim, 2-aminobenzothiazoly, sulfamethoxazole, and 4-amino antipyrine) and with minor amines such as Carbazol. By condensing Mannich bases made in part one with formaldehyde and phenol, the second stage included making phenol formaldehyde resin with Mannich bases. The synthesized resins (Phenol-formaldehyde) have been characterized. The characterization was done by (1H-NMR, and FT-IR) to determine the degree of biological activity associated with some of the active groups.Keywords: Carbazole, Mannich bases, phenol formaldehyde, polymerization and Resin.
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| format | Article |
| id | doaj-art-ad953808114c4e41af71a520ae97e7d8 |
| institution | Kabale University |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-ad953808114c4e41af71a520ae97e7d82025-08-20T03:35:24ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862024-12-01211210.21123/bsj.2024.8774Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological ActivityTamador Ali Mahmood 0Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad, Iraq. Mannich bases functional groups were used, which is considered an inventive phenol formaldehyde resin was created in this study. The project was divided into two phases. The first portion involves creating a monomer of Mannich bases through a condensation reaction. The reaction occurs between aromatic aldehyde (P-hydroxy benzaldehyde) and primary amines like (Metoclopramide, trimethoprim, 2-aminobenzothiazoly, sulfamethoxazole, and 4-amino antipyrine) and with minor amines such as Carbazol. By condensing Mannich bases made in part one with formaldehyde and phenol, the second stage included making phenol formaldehyde resin with Mannich bases. The synthesized resins (Phenol-formaldehyde) have been characterized. The characterization was done by (1H-NMR, and FT-IR) to determine the degree of biological activity associated with some of the active groups.Keywords: Carbazole, Mannich bases, phenol formaldehyde, polymerization and Resin. https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8774Biological activity, Carbazol, Mannich bases, Pharmaceutical Resins, Phenol formaldehyde. |
| spellingShingle | Tamador Ali Mahmood Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity مجلة بغداد للعلوم Biological activity, Carbazol, Mannich bases, Pharmaceutical Resins, Phenol formaldehyde. |
| title | Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity |
| title_full | Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity |
| title_fullStr | Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity |
| title_full_unstemmed | Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity |
| title_short | Synthesizing and Characterizing Some Pharmaceutical Resins Using Mannich Bases and Studying Their Biological Activity |
| title_sort | synthesizing and characterizing some pharmaceutical resins using mannich bases and studying their biological activity |
| topic | Biological activity, Carbazol, Mannich bases, Pharmaceutical Resins, Phenol formaldehyde. |
| url | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8774 |
| work_keys_str_mv | AT tamadoralimahmood synthesizingandcharacterizingsomepharmaceuticalresinsusingmannichbasesandstudyingtheirbiologicalactivity |