The feedback loop between miR-222-3p and ZEB1 harnesses metastasis in renal cell carcinoma

The feedback loop between miR-222-3p and ZEB1 harnesses metastasis in renal cell carcinoma

Abstract Renal cell carcinoma (RCC) is an aggressive malignancy originating from the renal parenchyma, often leading to high mortality due to local invasion and distant metastasis. MicroRNAs (miRNAs) play essential roles in RCC progression. Through miRNA sequencing, we identified significant upregul...

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Bibliographic Details
Main Authors: Fan Wang, Liao Li, Xiangfu Sun, Xianfu Cai, Jianjun Wang, Huiwen Luo, Yaodong Wang, Dong Ni, Decai Wang
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02385-0
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