Sorafenib Inhibits Tumor Growth and Improves Survival in a Transgenic Mouse Model of Pancreatic Islet Cell Tumors

Sorafenib Inhibits Tumor Growth and Improves Survival in a Transgenic Mouse Model of Pancreatic Islet Cell Tumors

Background. The purpose of the study was to evaluate Sorafenib (BAY 43-9006) derived receptor tyrosine kinase inhibition on tumor progression in murine islet cell tumors. Sorafenib is considered to be a potent inhibitor of tumor angiogenesis and neovascularization in various solid tumors. Rip1Tag2 m...

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Bibliographic Details
Main Authors:	Volker Fendrich, Katja Maschuw, Johannes Rehm, Malte Buchholz, Julia P. Holler, Emily P. Slater, Detlef K. Bartsch, Jens Waldmann
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1100/2012/529151
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