Fabrication and appraisal of targeted axitinib loaded bilosomes for the enhanced breast and ovarian anticancer activity.

Fabrication and appraisal of targeted axitinib loaded bilosomes for the enhanced breast and ovarian anticancer activity.

The goal of this study was the formulation and optimization by statistical means of bilosomal formulations of axitinib (AXT) in order to improve its anticancer efficacy in a targeted manner. A central composite rotatable design was employed Using Design-Expert® software. The formulation factors were...

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Bibliographic Details
Main Authors: Randa Mohammed Zaki, Basmah Nasser Aldosari, Layla A Alkharashi, Alyaa Alsalhi, Fatma I Abo El-Ela, Raneem Meshal Alosaimi, Maha Alsunbul, Obaid Afzal, Mayada Said
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325511
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