Monovalent Lectin Microvirin Utilizes Hydropathic Recognition of HIV-1 Env for Inhibition of Virus Cell Infection

Monovalent Lectin Microvirin Utilizes Hydropathic Recognition of HIV-1 Env for Inhibition of Virus Cell Infection

Microvirin is a lectin molecule known to have monovalent interaction with glycoprotein gp120. A previously reported high-resolution structural analysis defines the mannobiose-binding cavity of Microvirin. Nonetheless, structure does not directly define the energetics of binding contributions of prot...

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Bibliographic Details
Main Authors: Bibek Parajuli, Kriti Acharya, Harry Charles Bach, Shiyu Zhang, Cameron F. Abrams, Irwin Chaiken
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Viruses
Subjects:
SPR
epitope
Biacore
calorimetry
Sensorgram
ELISA
Online Access:https://www.mdpi.com/1999-4915/17/1/82
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