The Advantage of PET and CT Integration in Examination of Lung Tumors
Purpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and maximum standardized uptake value (SUVmax) in selected regions of interest (ROI) of lung masses. Materia...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2007/17131 |
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| _version_ | 1832556972494290944 |
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| author | Guangming Lu Zhongqiu Wang Hong Zhu Linfeng Chang Yingxin Chen Jiang Wu Yane Zhao |
| author_facet | Guangming Lu Zhongqiu Wang Hong Zhu Linfeng Chang Yingxin Chen Jiang Wu Yane Zhao |
| author_sort | Guangming Lu |
| collection | DOAJ |
| description | Purpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and maximum standardized uptake value (SUVmax) in selected regions of interest (ROI) of lung masses. Material and Methods. A retrospective analysis was performed on 85 patients with solid pulmonary lesions, all verified by pathology. The morphology, edge (speculated margins and lobule), size, density of pulmonary masses, and on-chest CT images were reviewed. The SUVmax in ROI of pulmonary masses was calculated. Results. Among the 85 patients with lung masses, 59 patients presented with pulmonary malignant neoplasm and 26 patients with benign lesions. The sensitivity, specificity, and accuracy were 89.8%, 61.5%, 81.2%, respectively, for PET measurement only, 88.1%, 65.4%, 81.2% for CT only, and 96.6%, 80.8%, 91.8% for PET/CT. The size of pulmonary malignant neoplasm in the 59 patients was apparently correlated with the ROI's SUVmax (r=0.617, P<.001). However, the size of pulmonary benign mass in the 26 patients was not correlated with the SUVmax. Conclusion. PET/CT is of greater value in characterization of lung masses than PET and CT performed separately. The examination of lung tumor can be further specified by the correlation between the size of pulmonary malignant neoplasm and the ROI's SUVmax. |
| format | Article |
| id | doaj-art-ad8208197b6241ea9aa571da6ec76972 |
| institution | Kabale University |
| issn | 1687-4188 1687-4196 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomedical Imaging |
| spelling | doaj-art-ad8208197b6241ea9aa571da6ec769722025-02-03T05:44:01ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962007-01-01200710.1155/2007/1713117131The Advantage of PET and CT Integration in Examination of Lung TumorsGuangming Lu0Zhongqiu Wang1Hong Zhu2Linfeng Chang3Yingxin Chen4Jiang Wu5Yane Zhao6Department of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaDepartment of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaDepartment of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaDepartment of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaDepartment of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaDepartment of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaDepartment of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, ChinaPurpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and maximum standardized uptake value (SUVmax) in selected regions of interest (ROI) of lung masses. Material and Methods. A retrospective analysis was performed on 85 patients with solid pulmonary lesions, all verified by pathology. The morphology, edge (speculated margins and lobule), size, density of pulmonary masses, and on-chest CT images were reviewed. The SUVmax in ROI of pulmonary masses was calculated. Results. Among the 85 patients with lung masses, 59 patients presented with pulmonary malignant neoplasm and 26 patients with benign lesions. The sensitivity, specificity, and accuracy were 89.8%, 61.5%, 81.2%, respectively, for PET measurement only, 88.1%, 65.4%, 81.2% for CT only, and 96.6%, 80.8%, 91.8% for PET/CT. The size of pulmonary malignant neoplasm in the 59 patients was apparently correlated with the ROI's SUVmax (r=0.617, P<.001). However, the size of pulmonary benign mass in the 26 patients was not correlated with the SUVmax. Conclusion. PET/CT is of greater value in characterization of lung masses than PET and CT performed separately. The examination of lung tumor can be further specified by the correlation between the size of pulmonary malignant neoplasm and the ROI's SUVmax.http://dx.doi.org/10.1155/2007/17131 |
| spellingShingle | Guangming Lu Zhongqiu Wang Hong Zhu Linfeng Chang Yingxin Chen Jiang Wu Yane Zhao The Advantage of PET and CT Integration in Examination of Lung Tumors International Journal of Biomedical Imaging |
| title | The Advantage of PET and CT Integration in Examination of Lung Tumors |
| title_full | The Advantage of PET and CT Integration in Examination of Lung Tumors |
| title_fullStr | The Advantage of PET and CT Integration in Examination of Lung Tumors |
| title_full_unstemmed | The Advantage of PET and CT Integration in Examination of Lung Tumors |
| title_short | The Advantage of PET and CT Integration in Examination of Lung Tumors |
| title_sort | advantage of pet and ct integration in examination of lung tumors |
| url | http://dx.doi.org/10.1155/2007/17131 |
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