Atypical Manifestation of DRESS Syndrome
The differential for liver transaminases over 1000 units/liter typically includes liver ischemia, acute viral hepatitis, acetaminophen toxicity, and autoimmune hepatitis. Prompt evaluation is imperative as these etiologies can lead to fulminant liver failure. We present a case of transaminases over...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/6863582 |
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| _version_ | 1832560688594157568 |
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| author | Christopher Hakim Constantine Melitas Eric Nguyen Kha Ngo |
| author_facet | Christopher Hakim Constantine Melitas Eric Nguyen Kha Ngo |
| author_sort | Christopher Hakim |
| collection | DOAJ |
| description | The differential for liver transaminases over 1000 units/liter typically includes liver ischemia, acute viral hepatitis, acetaminophen toxicity, and autoimmune hepatitis. Prompt evaluation is imperative as these etiologies can lead to fulminant liver failure. We present a case of transaminases over 1000 units/liter from an atypical etiology. A 52-year-old male, previously treated with allopurinol for an acute gout flare, presented with persistent fevers. Given that he had taken a “high-risk medication” 2–6 weeks before presentation, subsequently presented with fever, rash, renal impairment, elevated liver enzymes in the thousands, and peripheral eosinophilia, DRESS syndrome secondary to allopurinol was diagnosed. |
| format | Article |
| id | doaj-art-ad7e765c3a484282bdece5ddfe436639 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-ad7e765c3a484282bdece5ddfe4366392025-02-03T01:26:56ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362020-01-01202010.1155/2020/68635826863582Atypical Manifestation of DRESS SyndromeChristopher Hakim0Constantine Melitas1Eric Nguyen2Kha Ngo3Department of Internal Medicine, Ascension Providence Hospital, Michigan State University College of Human Medicine, Southfield, USADepartment of Gastroenterology, Ascension Providence Hospital, Michigan State University College of Human Medicine, Southfield, USAAmerican University of the Caribbean School of Medicine, Coral Gables, USADepartment of Gastroenterology, Ascension Providence Hospital, Michigan State University College of Human Medicine, Southfield, USAThe differential for liver transaminases over 1000 units/liter typically includes liver ischemia, acute viral hepatitis, acetaminophen toxicity, and autoimmune hepatitis. Prompt evaluation is imperative as these etiologies can lead to fulminant liver failure. We present a case of transaminases over 1000 units/liter from an atypical etiology. A 52-year-old male, previously treated with allopurinol for an acute gout flare, presented with persistent fevers. Given that he had taken a “high-risk medication” 2–6 weeks before presentation, subsequently presented with fever, rash, renal impairment, elevated liver enzymes in the thousands, and peripheral eosinophilia, DRESS syndrome secondary to allopurinol was diagnosed.http://dx.doi.org/10.1155/2020/6863582 |
| spellingShingle | Christopher Hakim Constantine Melitas Eric Nguyen Kha Ngo Atypical Manifestation of DRESS Syndrome Case Reports in Gastrointestinal Medicine |
| title | Atypical Manifestation of DRESS Syndrome |
| title_full | Atypical Manifestation of DRESS Syndrome |
| title_fullStr | Atypical Manifestation of DRESS Syndrome |
| title_full_unstemmed | Atypical Manifestation of DRESS Syndrome |
| title_short | Atypical Manifestation of DRESS Syndrome |
| title_sort | atypical manifestation of dress syndrome |
| url | http://dx.doi.org/10.1155/2020/6863582 |
| work_keys_str_mv | AT christopherhakim atypicalmanifestationofdresssyndrome AT constantinemelitas atypicalmanifestationofdresssyndrome AT ericnguyen atypicalmanifestationofdresssyndrome AT khango atypicalmanifestationofdresssyndrome |