Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials

Conclusions: We identified significant favorable effects of FGF21 analogs in improving lipid profiles and elevating circulating ADP levels in overweight and obese adults. Future studies are needed to evaluate the clinical benefits in this area of research.

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Main Authors: Zizheng Nie, Jiaoyang Xu, Yingying Liu, Qinglong Cao, Xinyi Qiu, Yiping Su, Shufen Han
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/ije/9943228
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author Zizheng Nie
Jiaoyang Xu
Yingying Liu
Qinglong Cao
Xinyi Qiu
Yiping Su
Shufen Han
author_facet Zizheng Nie
Jiaoyang Xu
Yingying Liu
Qinglong Cao
Xinyi Qiu
Yiping Su
Shufen Han
author_sort Zizheng Nie
collection DOAJ
description Conclusions: We identified significant favorable effects of FGF21 analogs in improving lipid profiles and elevating circulating ADP levels in overweight and obese adults. Future studies are needed to evaluate the clinical benefits in this area of research.
format Article
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institution DOAJ
issn 1687-8345
language English
publishDate 2025-01-01
publisher Wiley
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series International Journal of Endocrinology
spelling doaj-art-ad7b07053f31425eafe7a545db5ce02f2025-08-20T03:15:47ZengWileyInternational Journal of Endocrinology1687-83452025-01-01202510.1155/ije/9943228Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled TrialsZizheng Nie0Jiaoyang Xu1Yingying Liu2Qinglong Cao3Xinyi Qiu4Yiping Su5Shufen Han6School of Public Health and NursingSchool of Public Health and NursingSchool of Public Health and NursingSchool of Public Health and NursingSchool of Public Health and NursingDepartment of DermatologySchool of Public Health and NursingConclusions: We identified significant favorable effects of FGF21 analogs in improving lipid profiles and elevating circulating ADP levels in overweight and obese adults. Future studies are needed to evaluate the clinical benefits in this area of research.http://dx.doi.org/10.1155/ije/9943228
spellingShingle Zizheng Nie
Jiaoyang Xu
Yingying Liu
Qinglong Cao
Xinyi Qiu
Yiping Su
Shufen Han
Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials
International Journal of Endocrinology
title Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials
title_full Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials
title_fullStr Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials
title_full_unstemmed Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials
title_short Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials
title_sort effects and safety of fgf21 analogs on glycemic parameters lipid profiles and adiponectin in overweight and obese adults a meta analysis of randomized controlled trials
url http://dx.doi.org/10.1155/ije/9943228
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