An Investigation of the Anticancer Mechanism of <i>Caesalpinia sappan</i> L. Extract Against Colorectal Cancer by Integrating a Network Pharmacological Analysis and Experimental Validation

An Investigation of the Anticancer Mechanism of <i>Caesalpinia sappan</i> L. Extract Against Colorectal Cancer by Integrating a Network Pharmacological Analysis and Experimental Validation

<i>Caesalpinia sappan</i> L. has exhibited various pharmacological effects, yet its anticancer activities against colorectal cancer (CRC) and underlying molecular mechanisms remain unclear. This study investigated the anticancer properties of an ethanol extract of <i>C. sappan</...

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Bibliographic Details
Main Authors: Mibae Jeong, Jaemoo Chun, Sang-Min Park, Heerim Yeo, Se Won Na, In Jin Ha, Bonglee Kim, Mi-Kyung Jeong
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Plants
Subjects:
<i>Caesalpinia sappan</i> L.
colorectal cancer
network pharmacology
apoptosis
MC38 tumor
Online Access:https://www.mdpi.com/2223-7747/14/2/263
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