Molecular Circuits of Resolution in Renal Disease
Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting the cytokine milieu from proinflammatory to p...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2010.120 |
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| _version_ | 1849395287918903296 |
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| author | Emma Börgeson Catherine Godson |
| author_facet | Emma Börgeson Catherine Godson |
| author_sort | Emma Börgeson |
| collection | DOAJ |
| description | Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting the cytokine milieu from proinflammatory to proresolving and increasing the nonphlogistic phagocytosis of apoptotic cells by macrophages. Here we review the evidence for molecular circuits of resolution in renal disease. |
| format | Article |
| id | doaj-art-ad68d4c46e5842bebbe0e176b88b71e9 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-ad68d4c46e5842bebbe0e176b88b71e92025-08-20T03:39:40ZengWileyThe Scientific World Journal1537-744X2010-01-01101370138510.1100/tsw.2010.120Molecular Circuits of Resolution in Renal DiseaseEmma Börgeson0Catherine Godson1UCD Diabetes Research Centre, UCD Conway Institute, School of Medicine and Medical Sciences, University College Dublin, IrelandUCD Diabetes Research Centre, UCD Conway Institute, School of Medicine and Medical Sciences, University College Dublin, IrelandInflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting the cytokine milieu from proinflammatory to proresolving and increasing the nonphlogistic phagocytosis of apoptotic cells by macrophages. Here we review the evidence for molecular circuits of resolution in renal disease.http://dx.doi.org/10.1100/tsw.2010.120 |
| spellingShingle | Emma Börgeson Catherine Godson Molecular Circuits of Resolution in Renal Disease The Scientific World Journal |
| title | Molecular Circuits of Resolution in Renal Disease |
| title_full | Molecular Circuits of Resolution in Renal Disease |
| title_fullStr | Molecular Circuits of Resolution in Renal Disease |
| title_full_unstemmed | Molecular Circuits of Resolution in Renal Disease |
| title_short | Molecular Circuits of Resolution in Renal Disease |
| title_sort | molecular circuits of resolution in renal disease |
| url | http://dx.doi.org/10.1100/tsw.2010.120 |
| work_keys_str_mv | AT emmaborgeson molecularcircuitsofresolutioninrenaldisease AT catherinegodson molecularcircuitsofresolutioninrenaldisease |