PET imaging of platelet derived growth factor receptor β in lung fibrosis

PET imaging of platelet derived growth factor receptor β in lung fibrosis

Abstract Background Lung diseases such as idiopathic pulmonary fibrosis and acute respiratory distress syndrome (ARDS) are associated with significant morbidity and mortality, with limited treatment options. Platelet-derived growth factor receptor beta (PDGFRβ) signaling pathway is a key driver of f...

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Main Authors: Olivia Wegrzyniak, Francesco Lechi, Johanna Rokka, Bogdan Mitran, Bo Zhang, Ulrika Thelander, John Löfblom, Fredrik Y. Frejd, Olle Korsgren, Gaetano Perchiazzi, Jonas Eriksson, Olof Eriksson
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
PDGFRβ
Platelet-derived growth factor receptor beta
Pulmonary fibrosis
Pericytes
Positron emitted tomography
Molecular imaging
Online Access:https://doi.org/10.1186/s41181-025-00366-3
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