Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses

Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses

IntroductionPorcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most economically devastating pathogens in swine, primarily due to its extensive genetic diversity and lineage-dependent pathogenicity. Despite widespread vaccination, distinct PRRSV-2 lineages continue to cir...

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Main Authors: Gyeong-Seo Park, Seung-Chai Kim, Hwan-Ju Kim, Chang-Gi Jeong, Sang-Chul Kang, Go-Eun Shin, Seoung-Hee Kim, Hye-Young Jeong, Kyoung-Ki Lee, Sang-Myeong Lee, Won-Il Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
porcine reproductive and respiratory syndrome virus
Korean Lineage
pathogenicity
immune characteristics
host immunity
immune checkpoint molecules
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1599468/full
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