Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults

Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults

Background Calcific aortic valve disease (CAVD), and ensuing severe aortic stenosis (AS), is the foremost valvular disorder of aging, yet preventive therapies are lacking. A better understanding of the molecular underpinnings of aortic valve calcification (AVC) is necessary to develop pharmacologic...

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Main Authors: Anna E. Bortnick, Thomas R. Austin, Emily Hamerton, Valborg Gudmundsdottir, Valur Emilsson, Lori L. Jennings, Vilmundur Gudnason, David S. Owens, Daniele Massera, Line Dufresne, Ta‐Yu Yang, James C. Engert, George Thanassoulis, Russell P. Tracy, Robert E. Gerszten, Bruce M. Psaty, Jorge R. Kizer
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aortic stenosis
calcium
proteomics
valve
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.036336
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