Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment

Stereotactic radiotherapy (SRT) has become integral to modern oncology, offering the ability to deliver ablative doses while minimizing damage to surrounding normal tissues. Recent advancements in imaging integration, treatment planning, and dose delivery have expanded their clinical applications ac...

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Main Author: Atsuto Katano MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338251333658
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author Atsuto Katano MD, PhD
author_facet Atsuto Katano MD, PhD
author_sort Atsuto Katano MD, PhD
collection DOAJ
description Stereotactic radiotherapy (SRT) has become integral to modern oncology, offering the ability to deliver ablative doses while minimizing damage to surrounding normal tissues. Recent advancements in imaging integration, treatment planning, and dose delivery have expanded their clinical applications across various tumor types. However, challenges such as toxicity in anatomically critical regions, optimal margin determination, and the lack of standardized protocols persist. This review explores key issues in contemporary practice and highlights emerging clinical evidence across lung, liver, prostate, brain, and oligometastatic diseases. Further refinement in patient selection and treatment strategies is essential to maximize therapeutic efficacy and ensure safe implementation in broader clinical settings.
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spelling doaj-art-ad41af32e829422b88f45b5c64a214da2025-08-20T03:03:07ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382025-04-012410.1177/15330338251333658Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer TreatmentAtsuto Katano MD, PhDStereotactic radiotherapy (SRT) has become integral to modern oncology, offering the ability to deliver ablative doses while minimizing damage to surrounding normal tissues. Recent advancements in imaging integration, treatment planning, and dose delivery have expanded their clinical applications across various tumor types. However, challenges such as toxicity in anatomically critical regions, optimal margin determination, and the lack of standardized protocols persist. This review explores key issues in contemporary practice and highlights emerging clinical evidence across lung, liver, prostate, brain, and oligometastatic diseases. Further refinement in patient selection and treatment strategies is essential to maximize therapeutic efficacy and ensure safe implementation in broader clinical settings.https://doi.org/10.1177/15330338251333658
spellingShingle Atsuto Katano MD, PhD
Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment
Technology in Cancer Research & Treatment
title Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment
title_full Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment
title_fullStr Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment
title_full_unstemmed Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment
title_short Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment
title_sort exploring the current challenges and pioneering clinical applications of stereotactic radiotherapy in cancer treatment
url https://doi.org/10.1177/15330338251333658
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