Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil
To obtain experimental evidence on the therapeutic efficacy of essential oils in aromatherapy for inflammatory diseases, we examined the effects of geranium oil on carrageenan-induced and collagen II-induced inflammation in mice, to assess acute and chronic anti-inflammatory activities of the oil. S...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2006-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/MI/2006/62537 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832548076763480064 |
|---|---|
| author | Naho Maruyama Hiroko Ishibashi Weimin Hu Shinichiro Morofuji Shigeharu Inouye Hideyo Yamaguchi Shigeru Abe |
| author_facet | Naho Maruyama Hiroko Ishibashi Weimin Hu Shinichiro Morofuji Shigeharu Inouye Hideyo Yamaguchi Shigeru Abe |
| author_sort | Naho Maruyama |
| collection | DOAJ |
| description | To obtain experimental evidence on the therapeutic efficacy of essential oils in aromatherapy for inflammatory diseases, we examined the effects of geranium oil on carrageenan-induced and collagen II-induced inflammation in mice, to assess acute and chronic anti-inflammatory activities of the oil. Single intraperitoneal injection of 5 μL of geranium oil clearly suppressed the carrageenan-induced footpaw edema and increase in tissue myeloperoxidase activity, and repeated administration of the oil suppressed collagen-induced arthritis. These results revealed that geranium oil suppressed both acute and chronic inflammatory responses in mice. |
| format | Article |
| id | doaj-art-ad3cfe29d1cc4fb4b3ddd5cae8237fb4 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-ad3cfe29d1cc4fb4b3ddd5cae8237fb42025-02-03T06:42:16ZengWileyMediators of Inflammation0962-93511466-18612006-01-01200610.1155/MI/2006/6253762537Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium OilNaho Maruyama0Hiroko Ishibashi1Weimin Hu2Shinichiro Morofuji3Shigeharu Inouye4Hideyo Yamaguchi5Shigeru Abe6Institute of Medical Mycology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, JapanInstitute of Medical Mycology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, JapanInstitute of Medical Mycology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, JapanDepartment of Surgery, Teikyo University, 2-11-1, Kaga,Itabashi-ku, Tokyo 173-8605, JapanInstitute of Medical Mycology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, JapanInstitute of Medical Mycology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, JapanInstitute of Medical Mycology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, JapanTo obtain experimental evidence on the therapeutic efficacy of essential oils in aromatherapy for inflammatory diseases, we examined the effects of geranium oil on carrageenan-induced and collagen II-induced inflammation in mice, to assess acute and chronic anti-inflammatory activities of the oil. Single intraperitoneal injection of 5 μL of geranium oil clearly suppressed the carrageenan-induced footpaw edema and increase in tissue myeloperoxidase activity, and repeated administration of the oil suppressed collagen-induced arthritis. These results revealed that geranium oil suppressed both acute and chronic inflammatory responses in mice.http://dx.doi.org/10.1155/MI/2006/62537 |
| spellingShingle | Naho Maruyama Hiroko Ishibashi Weimin Hu Shinichiro Morofuji Shigeharu Inouye Hideyo Yamaguchi Shigeru Abe Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil Mediators of Inflammation |
| title | Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil |
| title_full | Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil |
| title_fullStr | Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil |
| title_full_unstemmed | Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil |
| title_short | Suppression of Carrageenan- and Collagen II-Induced Inflammation in Mice by Geranium Oil |
| title_sort | suppression of carrageenan and collagen ii induced inflammation in mice by geranium oil |
| url | http://dx.doi.org/10.1155/MI/2006/62537 |
| work_keys_str_mv | AT nahomaruyama suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil AT hirokoishibashi suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil AT weiminhu suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil AT shinichiromorofuji suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil AT shigeharuinouye suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil AT hideyoyamaguchi suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil AT shigeruabe suppressionofcarrageenanandcollageniiinducedinflammationinmicebygeraniumoil |