Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine

Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine

Abstract Background Oxysterols, gut metabolites, and N6-methyladenosine (m6A) are extensively implicated in the pathogenesis of cognitive dysfunction, while their alterations in different stages of mild cognitive impairment (MCI) have not been elucidated. Therefore, this study was conducted to explo...

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Bibliographic Details
Main Authors: Wenjing Feng, Mengwei Ju, Tao Wang, Shanshan Cui, Kexin Yang, Zhiting Guo, Miao Liu, Jiaxuan Tao, Huiyan Yu, Rong Xiao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Alzheimer’s Research & Therapy
Subjects:
Mild cognitive impairment
Oxysterols
Gut metabolites
N6-methyladenosine
Cognitive assessment
Online Access:https://doi.org/10.1186/s13195-025-01743-5
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