MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue

Abstract Stimulating adipose tissue thermogenesis has emerged as a promising strategy for combating obesity, with uncoupling protein 1 (UCP1) playing a central role in this process. However, the mechanisms that suppress adipose thermogenesis and energy dissipation in obesity are not fully understood...

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Main Authors: Xin‐Yuan Zhao, Ben‐Chi Zhao, Hui‐Lin Li, Ying Liu, Bei Wang, An‐Qi Li, Tian‐Shu Zeng, Hannah Xiaoyan Hui, Jia Sun, Domagoj Cikes, Nele Gheldof, Jorg Hager, Jian‐Xun Mi, D. Ross Laybutt, Yin‐Yue Deng, Yan‐Chuan Shi, G. Gregory Neely, Qiao‐Ping Wang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
adipose tissue
autophagy
mitochondrial carrier homolog 2 (MTCH2)
obesity
thermogenesis
Online Access:https://doi.org/10.1002/advs.202416598
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