Multiple drug-resistant HBV mutation may contribute to poor response of adefovir + entecavir in entecavir-resistant patients

Multiple drug-resistant HBV mutation may contribute to poor response of adefovir + entecavir in entecavir-resistant patients

Introduction: Adefovir plus entecavir (ADV+ETV) rescue therapy in ETV-resistant patients with chronic hepatitis B virus (HBV) infection is suboptimal in some patients. This study aims to elucidate the evolutionary characteristics of drug-resistant HBV mutants and their association with clinical res...

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Bibliographic Details
Main Authors: Jinman Shao, Yan Liu, Li-Ming Liu, Rongjuan Chen, Li Zhao, Yi Zhou, Le Li, Xiaodong Li, Jin Li, Dongping Xu
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2021-01-01
Series:Journal of Infection in Developing Countries
Subjects:
Hepatitis B virus
Entecavir-resistant
Multidrug-resistant
Mutation
Rescue therapy
Online Access:https://jidc.org/index.php/journal/article/view/12643
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