Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study

Abstract Objective To compare the efficacy of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in treating postvitrectomy cataracts. Methods Prospective randomized controlled study. Patients who underwent cataract surgery after pars plana vitrect...

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Main Authors: Lin Wen, Hao Lian, Yi Liu, Bin Wei, Yan Deng, Jianqi Hu, Ying Wu, Min Zhang, Yaoqin Fan, Li Xu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Ophthalmology
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Online Access:https://doi.org/10.1186/s12886-025-03871-w
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author Lin Wen
Hao Lian
Yi Liu
Bin Wei
Yan Deng
Jianqi Hu
Ying Wu
Min Zhang
Yaoqin Fan
Li Xu
author_facet Lin Wen
Hao Lian
Yi Liu
Bin Wei
Yan Deng
Jianqi Hu
Ying Wu
Min Zhang
Yaoqin Fan
Li Xu
author_sort Lin Wen
collection DOAJ
description Abstract Objective To compare the efficacy of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in treating postvitrectomy cataracts. Methods Prospective randomized controlled study. Patients who underwent cataract surgery after pars plana vitrectomy (PPV) were randomly divided into the FLACS group and the CPS group. Preoperative data of all patients were collected to compare intraoperative complications, average phacoemulsification energy (AVE), effective phacoemulsification time (EPT), postoperative intraocular pressure, corneal endothelial cell density (ECD), and best corrected visual acuity (BCVA). Results A total of 92 eyes were included in the analysis, with 47 eyes in the FLACS group and 45 eyes in the CPS group. The intraoperative AVEs and EPTs in the FLACS group were both lower than those in the CPS group (P < 0.05). In the FLACS group, incomplete prechopping and incomplete capsulorhexis occurred in 3 eyes (3/47, 6.38%), and incomplete lens dislocation occurred in 1 eye (1/47, 2.13%). In the CPS group, incomplete lens dislocation occurred in 2 eyes (2/45, 4.44%), and anterior capsule tears occurred in 1 eye (1/45, 2.22%). There was no statistically significant difference in intraoperative complications between the two groups (P > 0.05). Postoperatively, intraocular pressure (IOP) was lower in both groups than preoperatively, and there was no statistically significant difference in intraocular pressure between the two groups at three months postsurgery (P > 0.05). Three months postoperatively, the ECD in the FLACS group was greater than that in the CPS group, with less average endothelial cell loss (ECL) than that in the CPS group (P < 0.01). The BCVA in both groups improved to varying degrees compared with the preoperative values, with the FLACS group performing better than the CPS group on the first postoperative day (P < 0.05). There was no statistically significant difference between the two groups at one week, one month, or three months postoperatively (all P > 0.05). Conclusion FLACS is safe and effective for treating post-PPV cataracts and, compared with CPS, facilitates early postoperative recovery with no difference in final visual acuity. Residual silicone oil in the anterior chamber post-PPV may lead to certain specific outcomes for FLACS. Although it may not affect surgical results, it is still noteworthy.
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spelling doaj-art-ad18d2550aea46bcb8dab1799ad39ef92025-08-20T02:15:06ZengBMCBMC Ophthalmology1471-24152025-02-012511810.1186/s12886-025-03871-wEffect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled studyLin Wen0Hao Lian1Yi Liu2Bin Wei3Yan Deng4Jianqi Hu5Ying Wu6Min Zhang7Yaoqin Fan8Li Xu9Chengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalChengdu Aidi Eye HospitalAbstract Objective To compare the efficacy of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in treating postvitrectomy cataracts. Methods Prospective randomized controlled study. Patients who underwent cataract surgery after pars plana vitrectomy (PPV) were randomly divided into the FLACS group and the CPS group. Preoperative data of all patients were collected to compare intraoperative complications, average phacoemulsification energy (AVE), effective phacoemulsification time (EPT), postoperative intraocular pressure, corneal endothelial cell density (ECD), and best corrected visual acuity (BCVA). Results A total of 92 eyes were included in the analysis, with 47 eyes in the FLACS group and 45 eyes in the CPS group. The intraoperative AVEs and EPTs in the FLACS group were both lower than those in the CPS group (P < 0.05). In the FLACS group, incomplete prechopping and incomplete capsulorhexis occurred in 3 eyes (3/47, 6.38%), and incomplete lens dislocation occurred in 1 eye (1/47, 2.13%). In the CPS group, incomplete lens dislocation occurred in 2 eyes (2/45, 4.44%), and anterior capsule tears occurred in 1 eye (1/45, 2.22%). There was no statistically significant difference in intraoperative complications between the two groups (P > 0.05). Postoperatively, intraocular pressure (IOP) was lower in both groups than preoperatively, and there was no statistically significant difference in intraocular pressure between the two groups at three months postsurgery (P > 0.05). Three months postoperatively, the ECD in the FLACS group was greater than that in the CPS group, with less average endothelial cell loss (ECL) than that in the CPS group (P < 0.01). The BCVA in both groups improved to varying degrees compared with the preoperative values, with the FLACS group performing better than the CPS group on the first postoperative day (P < 0.05). There was no statistically significant difference between the two groups at one week, one month, or three months postoperatively (all P > 0.05). Conclusion FLACS is safe and effective for treating post-PPV cataracts and, compared with CPS, facilitates early postoperative recovery with no difference in final visual acuity. Residual silicone oil in the anterior chamber post-PPV may lead to certain specific outcomes for FLACS. Although it may not affect surgical results, it is still noteworthy.https://doi.org/10.1186/s12886-025-03871-wPars plana vitrectomyCataractFemtosecond laserPhacoemulsificationAverage phacoemulsification energyEffective phacoemulsification time
spellingShingle Lin Wen
Hao Lian
Yi Liu
Bin Wei
Yan Deng
Jianqi Hu
Ying Wu
Min Zhang
Yaoqin Fan
Li Xu
Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study
BMC Ophthalmology
Pars plana vitrectomy
Cataract
Femtosecond laser
Phacoemulsification
Average phacoemulsification energy
Effective phacoemulsification time
title Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study
title_full Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study
title_fullStr Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study
title_full_unstemmed Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study
title_short Effect of femtosecond laser-assisted cataract surgery for cataracts after pars plana vitrectomy: a prospective randomized controlled study
title_sort effect of femtosecond laser assisted cataract surgery for cataracts after pars plana vitrectomy a prospective randomized controlled study
topic Pars plana vitrectomy
Cataract
Femtosecond laser
Phacoemulsification
Average phacoemulsification energy
Effective phacoemulsification time
url https://doi.org/10.1186/s12886-025-03871-w
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