Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications

Abstract Alzheimer’s disease (AD) is among the most devastating neurodegenerative disorders with limited treatment options. Emerging evidence points to the involvement of lipid dysregulation in the development of AD. Nevertheless, the precise lipidomic landscape and the mechanistic roles of lipids i...

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Bibliographic Details
Main Authors: Sijia He, Ziying Xu, Xianlin Han
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-025-00803-6
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