Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten
The preparation of tritium-labeled Nβ-benzylpenicilloylalanine and its use as a monovalent hapten in binding studies is described. The binding of 10-8M hapten to antisera of various species is readily performed but insufficient test sensitivity hampers some potential applications. N-Benzylpenicillo...
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| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
1976-02-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/9289 |
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| _version_ | 1850283758802960384 |
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| author | U. Otz C.H. Schneider A.L. de Weck |
| author_facet | U. Otz C.H. Schneider A.L. de Weck |
| author_sort | U. Otz |
| collection | DOAJ |
| description |
The preparation of tritium-labeled Nβ-benzylpenicilloylalanine and its use as a monovalent hapten in binding studies is described. The binding of 10-8M hapten to antisera of various species is readily performed but insufficient test sensitivity hampers some potential applications. N-Benzylpenicilloyl-tyramine- J125 is another BPO-hapten of ready availability. Its binding capacity could however not be established thus far.
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| format | Article |
| id | doaj-art-ad0ad3c04e224eeabb3a9f87ac0dbedb |
| institution | OA Journals |
| issn | 0009-4293 2673-2424 |
| language | deu |
| publishDate | 1976-02-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj-art-ad0ad3c04e224eeabb3a9f87ac0dbedb2025-08-20T01:47:42ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241976-02-0130210.2533/chimia.1976.89Charakterisierung von Immunseren durch Bindung von monovalentem PenicilloylhaptenU. Otz0C.H. Schneider1A.L. de Weck2Institut für klinische Immunologie, Inselspital, BernInstitut für klinische Immunologie, Inselspital, BernInstitut für klinische Immunologie, Inselspital, Bern The preparation of tritium-labeled Nβ-benzylpenicilloylalanine and its use as a monovalent hapten in binding studies is described. The binding of 10-8M hapten to antisera of various species is readily performed but insufficient test sensitivity hampers some potential applications. N-Benzylpenicilloyl-tyramine- J125 is another BPO-hapten of ready availability. Its binding capacity could however not be established thus far. https://www.chimia.ch/chimia/article/view/9289 |
| spellingShingle | U. Otz C.H. Schneider A.L. de Weck Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten CHIMIA |
| title | Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten |
| title_full | Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten |
| title_fullStr | Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten |
| title_full_unstemmed | Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten |
| title_short | Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten |
| title_sort | charakterisierung von immunseren durch bindung von monovalentem penicilloylhapten |
| url | https://www.chimia.ch/chimia/article/view/9289 |
| work_keys_str_mv | AT uotz charakterisierungvonimmunserendurchbindungvonmonovalentempenicilloylhapten AT chschneider charakterisierungvonimmunserendurchbindungvonmonovalentempenicilloylhapten AT aldeweck charakterisierungvonimmunserendurchbindungvonmonovalentempenicilloylhapten |