Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis

Abstract Background Diabetic Cardiomyopathy (DCM) is a distinct form of heart disease whose pathogenesis remains largely elusive. Recent studies have shed light on the significant role of mitochondria in the development of DCM, emphasizing their critical involvement. Despite these advancements, a bi...

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Main Authors: Jiajie Li, Jinxing Liu, Yaping Wang, Heguo Yan, Qin Li, Weibo Wen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Hereditas
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Online Access:https://doi.org/10.1186/s41065-025-00488-3
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author Jiajie Li
Jinxing Liu
Yaping Wang
Heguo Yan
Qin Li
Weibo Wen
author_facet Jiajie Li
Jinxing Liu
Yaping Wang
Heguo Yan
Qin Li
Weibo Wen
author_sort Jiajie Li
collection DOAJ
description Abstract Background Diabetic Cardiomyopathy (DCM) is a distinct form of heart disease whose pathogenesis remains largely elusive. Recent studies have shed light on the significant role of mitochondria in the development of DCM, emphasizing their critical involvement. Despite these advancements, a bibliometric analysis focusing on the nexus between mitochondria and DCM has not been conducted, leaving a gap in a holistic understanding of research trends in this field. Methods This study extracted publications addressing the role of mitochondria in DCM from the Web of Science Core Collection, spanning from 1988 to 2024. A detailed bibliometric analysis was undertaken using tools like CiteSpace, VOSviewer, Microsoft Excel, and Tableau Public to assess the data. Results The analysis encompassed 440 publications involving 2705 researchers from 1457 institutions across 175 countries/regions. These studies were disseminated across 202 journals. China was the most prolific country with 192 publications, followed by the United States with 156, and Canada with 26. E. Dale Abel emerged as the most prolific author in this area. Key journals contributing to this research included the American Journal of Physiology-Heart and Circulatory Physiology and the Journal of Molecular and Cellular Cardiology. The future research direction is likely to focus deeper into the mechanisms of mitochondrial dysfunction in the diabetic heart and to identify molecular and cellular targets for therapeutic intervention. Conclusion This report presents the first detailed bibliometric review of the intersection between mitochondrial research and DCM. It offers critical insights and guidance for researchers aiming to navigate and contribute to this evolving area of study.
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spelling doaj-art-ad072f16e4e24194a3faf865cdff14ff2025-08-20T03:45:32ZengBMCHereditas1601-52232025-07-01162111410.1186/s41065-025-00488-3Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysisJiajie Li0Jinxing Liu1Yaping Wang2Heguo Yan3Qin Li4Weibo Wen5Yunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment, Yunnan University of Chinese MedicineSchool of Integrated Chinese and Western Medicine, Anhui University of Chinese MedicineSchool of Basic Medical Sciences, Yunnan University of Chinese MedicineYunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment, Yunnan University of Chinese MedicineYunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment, Yunnan University of Chinese MedicineYunnan Key Laboratory of Integrated Traditional Chinese and Western Medicine for Chronic Disease in Prevention and Treatment, Yunnan University of Chinese MedicineAbstract Background Diabetic Cardiomyopathy (DCM) is a distinct form of heart disease whose pathogenesis remains largely elusive. Recent studies have shed light on the significant role of mitochondria in the development of DCM, emphasizing their critical involvement. Despite these advancements, a bibliometric analysis focusing on the nexus between mitochondria and DCM has not been conducted, leaving a gap in a holistic understanding of research trends in this field. Methods This study extracted publications addressing the role of mitochondria in DCM from the Web of Science Core Collection, spanning from 1988 to 2024. A detailed bibliometric analysis was undertaken using tools like CiteSpace, VOSviewer, Microsoft Excel, and Tableau Public to assess the data. Results The analysis encompassed 440 publications involving 2705 researchers from 1457 institutions across 175 countries/regions. These studies were disseminated across 202 journals. China was the most prolific country with 192 publications, followed by the United States with 156, and Canada with 26. E. Dale Abel emerged as the most prolific author in this area. Key journals contributing to this research included the American Journal of Physiology-Heart and Circulatory Physiology and the Journal of Molecular and Cellular Cardiology. The future research direction is likely to focus deeper into the mechanisms of mitochondrial dysfunction in the diabetic heart and to identify molecular and cellular targets for therapeutic intervention. Conclusion This report presents the first detailed bibliometric review of the intersection between mitochondrial research and DCM. It offers critical insights and guidance for researchers aiming to navigate and contribute to this evolving area of study.https://doi.org/10.1186/s41065-025-00488-3Diabetic cardiomyopathyMitochondriaBibliometric analysisCitespaceVOSviewer
spellingShingle Jiajie Li
Jinxing Liu
Yaping Wang
Heguo Yan
Qin Li
Weibo Wen
Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis
Hereditas
Diabetic cardiomyopathy
Mitochondria
Bibliometric analysis
Citespace
VOSviewer
title Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis
title_full Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis
title_fullStr Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis
title_full_unstemmed Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis
title_short Global research trends in the relationship between diabetic cardiomyopathy and mitochondria: a bibliometric analysis
title_sort global research trends in the relationship between diabetic cardiomyopathy and mitochondria a bibliometric analysis
topic Diabetic cardiomyopathy
Mitochondria
Bibliometric analysis
Citespace
VOSviewer
url https://doi.org/10.1186/s41065-025-00488-3
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