A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment
Snakebites are a severe medical and social issue, particularly in tropical and subtropical countries with minimal medical facilities, where the most dangerous snakes are found. Worldwide, most rural areas use medicinal plants alone or in combination as antidotes for snakebite treatment. Local knowle...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1548929/full |
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| author | Ashish Kumar Rameshwari A. Banjara Roman Kumar Aneshwari Junaid Khan Paulo Sergio Bernarde |
| author_facet | Ashish Kumar Rameshwari A. Banjara Roman Kumar Aneshwari Junaid Khan Paulo Sergio Bernarde |
| author_sort | Ashish Kumar |
| collection | DOAJ |
| description | Snakebites are a severe medical and social issue, particularly in tropical and subtropical countries with minimal medical facilities, where the most dangerous snakes are found. Worldwide, most rural areas use medicinal plants alone or in combination as antidotes for snakebite treatment. Local knowledge of medicinal plants for snakebite treatment plays a more critical role in primary healthcare services in rural areas. As a result of this review, it is revealed that 39% of herbs, 38% of shrubs, 18% of trees, 2% of climbers, 2% of bulbs, and 1% of ferns have snake antivenom potential, which is indicative of the presence of numerous phytochemicals such as alkaloids, coumarins, curcuminoids, flavonoids, steroids, triterpenoids, and cinnamic acid in particular plants. According to the availability of information, the data focus on the plants, their families, and their parts from various literature sources. In the future, the valuable plants reported here and their phytoconstituents may be potential sources for developing effective natural drugs for snake bite treatments. Therefore, this review is a comprehensive study of the snake antivenom potential of various medicinal plants and their bioactive compounds. |
| format | Article |
| id | doaj-art-acfa8c8dfa774ea6ab530f553fb65110 |
| institution | Kabale University |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-acfa8c8dfa774ea6ab530f553fb651102025-08-20T03:39:57ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-03-011610.3389/fphar.2025.15489291548929A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatmentAshish Kumar0Rameshwari A. Banjara1Roman Kumar Aneshwari2Junaid Khan3Paulo Sergio Bernarde4Department of Biotechnology, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Chhattisgarh, IndiaDepartment of Chemistry, Rajeev Gandhi Government Postgraduate College, Ambikapur, Chhattisgarh, IndiaSchool of Pharmacy, MATS University, Raipur, Chhattisgarh, IndiaDepartment of Pharmacy, Sant Gahira Guru Vishwavidyalaya, Sarguja Ambikapur, Chhattisgarh, IndiaLaboratório de Herpetologia, Centro Multidisciplinar, Campus Floresta, Universidade Federal do Acre, Cruzeiro do Sul, Acre, BrazilSnakebites are a severe medical and social issue, particularly in tropical and subtropical countries with minimal medical facilities, where the most dangerous snakes are found. Worldwide, most rural areas use medicinal plants alone or in combination as antidotes for snakebite treatment. Local knowledge of medicinal plants for snakebite treatment plays a more critical role in primary healthcare services in rural areas. As a result of this review, it is revealed that 39% of herbs, 38% of shrubs, 18% of trees, 2% of climbers, 2% of bulbs, and 1% of ferns have snake antivenom potential, which is indicative of the presence of numerous phytochemicals such as alkaloids, coumarins, curcuminoids, flavonoids, steroids, triterpenoids, and cinnamic acid in particular plants. According to the availability of information, the data focus on the plants, their families, and their parts from various literature sources. In the future, the valuable plants reported here and their phytoconstituents may be potential sources for developing effective natural drugs for snake bite treatments. Therefore, this review is a comprehensive study of the snake antivenom potential of various medicinal plants and their bioactive compounds.https://www.frontiersin.org/articles/10.3389/fphar.2025.1548929/fullsnakebitesnake venomethnomedicinemedicinal plantsphytoconstituents |
| spellingShingle | Ashish Kumar Rameshwari A. Banjara Roman Kumar Aneshwari Junaid Khan Paulo Sergio Bernarde A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment Frontiers in Pharmacology snakebite snake venom ethnomedicine medicinal plants phytoconstituents |
| title | A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment |
| title_full | A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment |
| title_fullStr | A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment |
| title_full_unstemmed | A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment |
| title_short | A comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment |
| title_sort | comprehensive review on recent advances in the use of ethnomedicinal plants and their metabolites in snake bite treatment |
| topic | snakebite snake venom ethnomedicine medicinal plants phytoconstituents |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2025.1548929/full |
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