A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection
Signet-ring cell carcinoma (SRCC) is a rare tumor that most commonly occurs in the stomach. Duodenal SRCCs are extremely uncommon and account for approximately 1% of duodenal adenocarcinomas. Although Brunner’s gland hyperplasia (BGH) is a benign duodenal condition, studies have reported several cas...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean College of Helicobacter and Upper Gastrointestinal Research
2024-06-01
|
| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| Subjects: | |
| Online Access: | http://helicojournal.org/upload/pdf/kjhugr-2024-0014.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849250803313803264 |
|---|---|
| author | Hae Rin Lee Bong Eun Lee Kyung Bin Kim Gwang Ha Kim Moon Won Lee Dong Chan Joo |
| author_facet | Hae Rin Lee Bong Eun Lee Kyung Bin Kim Gwang Ha Kim Moon Won Lee Dong Chan Joo |
| author_sort | Hae Rin Lee |
| collection | DOAJ |
| description | Signet-ring cell carcinoma (SRCC) is a rare tumor that most commonly occurs in the stomach. Duodenal SRCCs are extremely uncommon and account for approximately 1% of duodenal adenocarcinomas. Although Brunner’s gland hyperplasia (BGH) is a benign duodenal condition, studies have reported several cases of adenocarcinoma originating in an area of BGH. We report a rare case of early-stage SRCC originating in an area of BGH that was successfully treated using endoscopic mucosal resection. Based on the mucin phenotype observed in this case, it is reasonable to conclude that SRCC originated from gastric metaplasia in the area of BGH. Although BGH is a benign condition, careful evaluation is warranted for early detection of combined neoplasms. |
| format | Article |
| id | doaj-art-acf3ed644e0f42d2bd82f386f3a8e3d7 |
| institution | Kabale University |
| issn | 1738-3331 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-acf3ed644e0f42d2bd82f386f3a8e3d72025-08-20T03:57:09ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312024-06-0124218218610.7704/kjhugr.2024.0014842A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic ResectionHae Rin Lee0Bong Eun Lee1Kyung Bin Kim2Gwang Ha Kim3Moon Won Lee4Dong Chan Joo5 Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Pathology, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, KoreaSignet-ring cell carcinoma (SRCC) is a rare tumor that most commonly occurs in the stomach. Duodenal SRCCs are extremely uncommon and account for approximately 1% of duodenal adenocarcinomas. Although Brunner’s gland hyperplasia (BGH) is a benign duodenal condition, studies have reported several cases of adenocarcinoma originating in an area of BGH. We report a rare case of early-stage SRCC originating in an area of BGH that was successfully treated using endoscopic mucosal resection. Based on the mucin phenotype observed in this case, it is reasonable to conclude that SRCC originated from gastric metaplasia in the area of BGH. Although BGH is a benign condition, careful evaluation is warranted for early detection of combined neoplasms.http://helicojournal.org/upload/pdf/kjhugr-2024-0014.pdfduodenumbrunner’s glandcarcinoma, signet ring cellendoscopic mucosal resection |
| spellingShingle | Hae Rin Lee Bong Eun Lee Kyung Bin Kim Gwang Ha Kim Moon Won Lee Dong Chan Joo A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection The Korean Journal of Helicobacter and Upper Gastrointestinal Research duodenum brunner’s gland carcinoma, signet ring cell endoscopic mucosal resection |
| title | A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection |
| title_full | A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection |
| title_fullStr | A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection |
| title_full_unstemmed | A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection |
| title_short | A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection |
| title_sort | rare case of signet ring cell carcinoma arising on duodenal brunner s gland hyperplasia successfully treated via endoscopic resection |
| topic | duodenum brunner’s gland carcinoma, signet ring cell endoscopic mucosal resection |
| url | http://helicojournal.org/upload/pdf/kjhugr-2024-0014.pdf |
| work_keys_str_mv | AT haerinlee ararecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT bongeunlee ararecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT kyungbinkim ararecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT gwanghakim ararecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT moonwonlee ararecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT dongchanjoo ararecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT haerinlee rarecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT bongeunlee rarecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT kyungbinkim rarecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT gwanghakim rarecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT moonwonlee rarecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection AT dongchanjoo rarecaseofsignetringcellcarcinomaarisingonduodenalbrunnersglandhyperplasiasuccessfullytreatedviaendoscopicresection |