Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study

Background: The use of spinal anesthesia in patients undergoing cesarean section (CS) is at risk of experiencing post-dural puncture headache (PDPH). This is influenced by several factors. Objective: This study aimed to assess the effect of risk factors on the occurrence of PDPH in patients undergo...

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Main Authors: Widya Istanto Nurcahyo, Johan Arifin, Doso Sutiyono, Bondan Irtani Cahyadi, Dina Paramita, Taufik Eko Nugroho, Chandra Hermawan Manapa, Indra Kusuma
Format: Article
Language:English
Published: Fakultas Kedokteran, Universitas Diponegoro 2024-03-01
Series:JAI (Jurnal Anestesiologi Indonesia)
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Online Access:https://ejournal.undip.ac.id/index.php/janesti/article/view/61657
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author Widya Istanto Nurcahyo
Johan Arifin
Doso Sutiyono
Bondan Irtani Cahyadi
Dina Paramita
Taufik Eko Nugroho
Chandra Hermawan Manapa
Indra Kusuma
author_facet Widya Istanto Nurcahyo
Johan Arifin
Doso Sutiyono
Bondan Irtani Cahyadi
Dina Paramita
Taufik Eko Nugroho
Chandra Hermawan Manapa
Indra Kusuma
author_sort Widya Istanto Nurcahyo
collection DOAJ
description Background: The use of spinal anesthesia in patients undergoing cesarean section (CS) is at risk of experiencing post-dural puncture headache (PDPH). This is influenced by several factors. Objective: This study aimed to assess the effect of risk factors on the occurrence of PDPH in patients undergoing CS under spinal anesthesia. Methods: The study design is a nested case-control study with independent variables influencing the incidence of PDPH in CS with spinal anesthesia. Samples were taken from CS patients with spinal anesthesia at the Central Surgical Installation of Dr. Kariadi General Hospital, who met the inclusion and exclusion criteria. Result: A total of 74 patients were included in the multivariate analysis, which showed that neurological disorders with p-value = 0.069; OR= 9,306; 95% CI = 0.842-102.828 and the number of punctures with p = 0.060; OR= 4.798; 95% CI = 0.997-23.075 is the most significant risk factor for the incidence of PDPH in CS patients. There was an additive effect which indicated that mobilization of more than 6 hours mutually reinforces the occurrence of PDPH in CS patients. Conclusion: Preoperative risk factors such as a history of neurological disorders increase the incidence of PDPH in CS patients. Intraoperative risk factors in this study were total puncture and needle size, increasing the incidence of PDPH in CS patients. Post-operative risk factors, in this case, immobilization, increase the incidence of PDPH in CS patients. Preoperative, intraoperative, and post-operative risk factors, together or separately, increase the incidence of PDPH in patients undergoing CS.
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issn 2337-5124
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language English
publishDate 2024-03-01
publisher Fakultas Kedokteran, Universitas Diponegoro
record_format Article
series JAI (Jurnal Anestesiologi Indonesia)
spelling doaj-art-ace479e255984fe9bfef574bb66dc46e2025-08-20T02:38:06ZengFakultas Kedokteran, Universitas DiponegoroJAI (Jurnal Anestesiologi Indonesia)2337-51242089-970X2024-03-01161142510.14710/jai.v0i0.6165723726Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis StudyWidya Istanto Nurcahyo0https://orcid.org/0000-0003-0550-5625Johan Arifin1Doso Sutiyono2Bondan Irtani Cahyadi3Dina Paramita4Taufik Eko Nugroho5Chandra Hermawan Manapa6Indra Kusuma7Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, IndonesiaDepartment of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, IndonesiaDepartment of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, IndonesiaDepartment of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, IndonesiaDepartment of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, IndonesiaDepartment of Anesthesiology and Intensive Therapy, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, IndonesiaFaculty of Medicine, Diponegoro University, Semarang, IndonesiaFaculty of Medicine, Diponegoro University, Semarang, IndonesiaBackground: The use of spinal anesthesia in patients undergoing cesarean section (CS) is at risk of experiencing post-dural puncture headache (PDPH). This is influenced by several factors. Objective: This study aimed to assess the effect of risk factors on the occurrence of PDPH in patients undergoing CS under spinal anesthesia. Methods: The study design is a nested case-control study with independent variables influencing the incidence of PDPH in CS with spinal anesthesia. Samples were taken from CS patients with spinal anesthesia at the Central Surgical Installation of Dr. Kariadi General Hospital, who met the inclusion and exclusion criteria. Result: A total of 74 patients were included in the multivariate analysis, which showed that neurological disorders with p-value = 0.069; OR= 9,306; 95% CI = 0.842-102.828 and the number of punctures with p = 0.060; OR= 4.798; 95% CI = 0.997-23.075 is the most significant risk factor for the incidence of PDPH in CS patients. There was an additive effect which indicated that mobilization of more than 6 hours mutually reinforces the occurrence of PDPH in CS patients. Conclusion: Preoperative risk factors such as a history of neurological disorders increase the incidence of PDPH in CS patients. Intraoperative risk factors in this study were total puncture and needle size, increasing the incidence of PDPH in CS patients. Post-operative risk factors, in this case, immobilization, increase the incidence of PDPH in CS patients. Preoperative, intraoperative, and post-operative risk factors, together or separately, increase the incidence of PDPH in patients undergoing CS.https://ejournal.undip.ac.id/index.php/janesti/article/view/61657cesarean sectionearly mobilizationpost-dural puncture headacherisk of post-dural puncture headacherisk of spinal anesthesia
spellingShingle Widya Istanto Nurcahyo
Johan Arifin
Doso Sutiyono
Bondan Irtani Cahyadi
Dina Paramita
Taufik Eko Nugroho
Chandra Hermawan Manapa
Indra Kusuma
Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study
JAI (Jurnal Anestesiologi Indonesia)
cesarean section
early mobilization
post-dural puncture headache
risk of post-dural puncture headache
risk of spinal anesthesia
title Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study
title_full Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study
title_fullStr Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study
title_full_unstemmed Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study
title_short Risk Factors of Post Dural Puncture Headache in Cesarean Section Patients: A Multivariate Analysis Study
title_sort risk factors of post dural puncture headache in cesarean section patients a multivariate analysis study
topic cesarean section
early mobilization
post-dural puncture headache
risk of post-dural puncture headache
risk of spinal anesthesia
url https://ejournal.undip.ac.id/index.php/janesti/article/view/61657
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