Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System

Background. The Nellix endovascular sealing system (EVAS) was a unique concept with regard to its sealing concept that failed, related to high migration rates. We investigated the changes in aortoiliac morphology during the cardiac cycle before and after EVAS using electrocardiography (ECG)-gated CT...

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Main Authors: Leo H. Van Den Ham, Talar Lazarian, Erik Groot Jebbink, Jan-Willem Lardenoije, Clark J. Zeebregts, Michel M. P. J. Reijnen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Radiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2023/3721185
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author Leo H. Van Den Ham
Talar Lazarian
Erik Groot Jebbink
Jan-Willem Lardenoije
Clark J. Zeebregts
Michel M. P. J. Reijnen
author_facet Leo H. Van Den Ham
Talar Lazarian
Erik Groot Jebbink
Jan-Willem Lardenoije
Clark J. Zeebregts
Michel M. P. J. Reijnen
author_sort Leo H. Van Den Ham
collection DOAJ
description Background. The Nellix endovascular sealing system (EVAS) was a unique concept with regard to its sealing concept that failed, related to high migration rates. We investigated the changes in aortoiliac morphology during the cardiac cycle before and after EVAS using electrocardiography (ECG)-gated CT. Methods. Eight patients scheduled for EVAS were prospectively enrolled. ECG-gated CT scans were made pre- and postoperatively. Measurements were performed in the mid-systolic and mid-diastolic phases. Endpoints were changes in infrarenal aortoiliac morphology postoperatively compared to preoperatively and their changes in the cardiac cycle. Results. Both pre- and postoperatively, there were no changes during the cardiac cycle. EVAS caused an increase in neck diameter and surface in both phases (p<0.001). EVAS increased the luminal AAA volume (p<0.001), with a decrease in thrombus volume (p<0.001) in both phases and an increase in total volume (p<0.001) in the systolic phase. During follow-up, one patient presented with >5 mm migration. There were no differences in the movements of this patient compared to the remaining patients. Conclusion. The cardiac cycle had a very limited effect on the aortoiliac dynamics before and after EVAS and, therefore, there is probably not a role for ECG-gated CT in enhanced surveillance programs. EVAS itself has a significant impact on anatomy, particularly the neck diameter, length, and volumes of the AAA.
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spelling doaj-art-ace31d54ca284673a15214a6bb9865d02025-08-20T03:38:58ZengWileyRadiology Research and Practice2090-195X2023-01-01202310.1155/2023/3721185Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing SystemLeo H. Van Den Ham0Talar Lazarian1Erik Groot Jebbink2Jan-Willem Lardenoije3Clark J. Zeebregts4Michel M. P. J. Reijnen5Department of SurgeryDepartment of SurgeryDepartment of SurgeryDepartment of SurgeryDepartment of SurgeryDepartment of SurgeryBackground. The Nellix endovascular sealing system (EVAS) was a unique concept with regard to its sealing concept that failed, related to high migration rates. We investigated the changes in aortoiliac morphology during the cardiac cycle before and after EVAS using electrocardiography (ECG)-gated CT. Methods. Eight patients scheduled for EVAS were prospectively enrolled. ECG-gated CT scans were made pre- and postoperatively. Measurements were performed in the mid-systolic and mid-diastolic phases. Endpoints were changes in infrarenal aortoiliac morphology postoperatively compared to preoperatively and their changes in the cardiac cycle. Results. Both pre- and postoperatively, there were no changes during the cardiac cycle. EVAS caused an increase in neck diameter and surface in both phases (p<0.001). EVAS increased the luminal AAA volume (p<0.001), with a decrease in thrombus volume (p<0.001) in both phases and an increase in total volume (p<0.001) in the systolic phase. During follow-up, one patient presented with >5 mm migration. There were no differences in the movements of this patient compared to the remaining patients. Conclusion. The cardiac cycle had a very limited effect on the aortoiliac dynamics before and after EVAS and, therefore, there is probably not a role for ECG-gated CT in enhanced surveillance programs. EVAS itself has a significant impact on anatomy, particularly the neck diameter, length, and volumes of the AAA.http://dx.doi.org/10.1155/2023/3721185
spellingShingle Leo H. Van Den Ham
Talar Lazarian
Erik Groot Jebbink
Jan-Willem Lardenoije
Clark J. Zeebregts
Michel M. P. J. Reijnen
Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System
Radiology Research and Practice
title Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System
title_full Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System
title_fullStr Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System
title_full_unstemmed Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System
title_short Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System
title_sort evaluation of electrocardiogram gated computed tomography angiography to quantify changes in geometry and dynamic behavior during the cardiac cycle of the nellix endovascular sealing system
url http://dx.doi.org/10.1155/2023/3721185
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