How does biological age acceleration mediate the associations of obesity with cardiovascular disease? Evidence from international multi-cohort studies

How does biological age acceleration mediate the associations of obesity with cardiovascular disease? Evidence from international multi-cohort studies

Abstract Background Recent basic biological research found that obesity accelerates biological aging and increases cardiovascular disease (CVD) risk. However, there is still a lack of real-world population evidence. This study aimed to explore the potential mediation roles of biological age accelera...

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Bibliographic Details
Main Authors: Lin Hu, Jiayuan Li, Zihuan Tang, Peng Gong, Zongqi Chang, Chen Yang, Tianpei Ma, Shuang Jiang, Chunxia Yang, Tao Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cardiovascular Diabetology
Subjects:
Biological age acceleration
Obesity
Cardiovascular disease
Cohort
Online Access:https://doi.org/10.1186/s12933-025-02770-0
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