Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions

The increasing demand for natural flavor enhancers and functional food ingredients has driven interest in Lentinus edodes (shiitake mushrooms), which are rich in proteins and bioactive compounds. This study optimized the enzymatic hydrolysis of L. edodes using various proteases and response surface...

Full description

Saved in:
Bibliographic Details
Main Authors: Bowei Zheng, Xiaoqi Wu, Tonglei Qiao, Qiang Ding, Honglei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Sustainable Food Systems
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsufs.2025.1617816/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850111057827201024
author Bowei Zheng
Xiaoqi Wu
Tonglei Qiao
Qiang Ding
Honglei Wang
author_facet Bowei Zheng
Xiaoqi Wu
Tonglei Qiao
Qiang Ding
Honglei Wang
author_sort Bowei Zheng
collection DOAJ
description The increasing demand for natural flavor enhancers and functional food ingredients has driven interest in Lentinus edodes (shiitake mushrooms), which are rich in proteins and bioactive compounds. This study optimized the enzymatic hydrolysis of L. edodes using various proteases and response surface methodology. Single-factor experiments were conducted, and flavor protease was identified as the most effective enzyme. The optimal hydrolysis conditions were 50.268°C, 5.23% material ratio, and 223.64 kU/100 g protease dosage, with a predicted amino acid nitrogen raise ratio of 268.908%. Validation tests gave an average of 267.6 ± 0.7%, with <5% deviation. After hydrolysis, glutamic acid, aspartic acid, and alanine increased, enhancing umami and sweetness. Essential amino acids such as lysine, valine, and isoleucine also rose significantly. Antioxidant activity was confirmed by DPPH and ·O₂- scavenging, with IC₅₀ values of 2.536 and 2.013, respectively. These results demonstrate that enzymatic hydrolysis is a promising approach to improve both the taste and nutritional value of L. edodes, supporting its application in natural seasoning and functional food development.
format Article
id doaj-art-acdd3c2f5ce24eb494f2790e34fbdcc4
institution OA Journals
issn 2571-581X
language English
publishDate 2025-06-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Sustainable Food Systems
spelling doaj-art-acdd3c2f5ce24eb494f2790e34fbdcc42025-08-20T02:37:42ZengFrontiers Media S.A.Frontiers in Sustainable Food Systems2571-581X2025-06-01910.3389/fsufs.2025.16178161617816Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functionsBowei ZhengXiaoqi WuTonglei QiaoQiang DingHonglei WangThe increasing demand for natural flavor enhancers and functional food ingredients has driven interest in Lentinus edodes (shiitake mushrooms), which are rich in proteins and bioactive compounds. This study optimized the enzymatic hydrolysis of L. edodes using various proteases and response surface methodology. Single-factor experiments were conducted, and flavor protease was identified as the most effective enzyme. The optimal hydrolysis conditions were 50.268°C, 5.23% material ratio, and 223.64 kU/100 g protease dosage, with a predicted amino acid nitrogen raise ratio of 268.908%. Validation tests gave an average of 267.6 ± 0.7%, with <5% deviation. After hydrolysis, glutamic acid, aspartic acid, and alanine increased, enhancing umami and sweetness. Essential amino acids such as lysine, valine, and isoleucine also rose significantly. Antioxidant activity was confirmed by DPPH and ·O₂- scavenging, with IC₅₀ values of 2.536 and 2.013, respectively. These results demonstrate that enzymatic hydrolysis is a promising approach to improve both the taste and nutritional value of L. edodes, supporting its application in natural seasoning and functional food development.https://www.frontiersin.org/articles/10.3389/fsufs.2025.1617816/fullmushroom proteinamino acid evaluationresponse surfaceprotease hydrolysisflavorTAV value
spellingShingle Bowei Zheng
Xiaoqi Wu
Tonglei Qiao
Qiang Ding
Honglei Wang
Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions
Frontiers in Sustainable Food Systems
mushroom protein
amino acid evaluation
response surface
protease hydrolysis
flavor
TAV value
title Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions
title_full Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions
title_fullStr Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions
title_full_unstemmed Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions
title_short Response surface methodology optimization of enzymatic hydrolysis of Lentinus edodes and analysis of product ingredients functions
title_sort response surface methodology optimization of enzymatic hydrolysis of lentinus edodes and analysis of product ingredients functions
topic mushroom protein
amino acid evaluation
response surface
protease hydrolysis
flavor
TAV value
url https://www.frontiersin.org/articles/10.3389/fsufs.2025.1617816/full
work_keys_str_mv AT boweizheng responsesurfacemethodologyoptimizationofenzymatichydrolysisoflentinusedodesandanalysisofproductingredientsfunctions
AT xiaoqiwu responsesurfacemethodologyoptimizationofenzymatichydrolysisoflentinusedodesandanalysisofproductingredientsfunctions
AT tongleiqiao responsesurfacemethodologyoptimizationofenzymatichydrolysisoflentinusedodesandanalysisofproductingredientsfunctions
AT qiangding responsesurfacemethodologyoptimizationofenzymatichydrolysisoflentinusedodesandanalysisofproductingredientsfunctions
AT hongleiwang responsesurfacemethodologyoptimizationofenzymatichydrolysisoflentinusedodesandanalysisofproductingredientsfunctions