Ibuprofen prevents the conjugative transfer of plasmid-mediated antimicrobial resistance genes
Refractory infections caused by multidrug-resistant bacteria pose a significant threat to public health. Here we report that ibuprofen inhibits conjugation of the RP4 plasmid and plasmids from clinical strains carrying different resistance genes including mcr-1, blaNDM, blaKPC, tet(X4), and tmexCD1-...
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| Main Authors: | Guangfen Zhang, Chunli Li, Xiaofan Li, Yuanyuan Li, Yunbing Li, Xiangkun Zeng, Chen Xu, Shuyan Wu, Ning Dong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
|
| Series: | Journal of Global Antimicrobial Resistance |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213716525000153 |
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