Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis

Background: Liver metastasis is a leading cause of colorectal cancer mortality. Therefore, the underlying mechanism and potential therapeutic target of colorectal cancer liver metastasis urge to be found. Mounting evidence indicates that cancer-derived sialylated IgG promotes tumor formation and pro...

Full description

Saved in:
Bibliographic Details
Main Authors: Jing Chen, Shenghua Zhang, Xinmei Huang, Qianqian Wang, Weiyan Xu, Jing Huang, Yuming Su, Qinkun Sun, Xiaojuan Du, Baocai Xing, Xiaoyan Qiu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000193
Tags: Add Tag
No Tags, Be the first to tag this record!