An emerging role for neutrophils in the pathogenesis of endometriosis
Abstract Endometriosis is a chronic gynecological disease negatively impacting the health of women and is characterized by the presence of ectopic endometrial-like lesions. The immune system is implicated in endometriosis pathogenesis by promoting endometrial cell survival and creating a microenviro...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
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| Series: | npj Women's Health |
| Online Access: | https://doi.org/10.1038/s44294-025-00059-x |
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| Summary: | Abstract Endometriosis is a chronic gynecological disease negatively impacting the health of women and is characterized by the presence of ectopic endometrial-like lesions. The immune system is implicated in endometriosis pathogenesis by promoting endometrial cell survival and creating a microenvironment for lesion development and growth. Neutrophils are phagocytic cells that degranulate, form neutrophil extracellular traps, and recruit immune cells to lesions. Herein we discuss the roles of neutrophils in endometriosis pathogenesis. |
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| ISSN: | 2948-1716 |