First-line treatment of hepatocellular carcinoma: a propensity-matched analysis of tyrosine kinase inhibitors combined with TACE, with or without PD-1 inhibitors

First-line treatment of hepatocellular carcinoma: a propensity-matched analysis of tyrosine kinase inhibitors combined with TACE, with or without PD-1 inhibitors

ObjectiveThis study attempted to comprehensively assess the clinical outcomes of cases with progressive HCC (pHCC) undergoing treatment with TKI and ICI in conjunction with TACE, as compared to the combination of TKI with TACE alone.MethodsFrom March 2019 to January 2022, this cohort comprised 82 ca...

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Bibliographic Details
Main Authors: Yanjun Shen, Yawen Xu, Ying Teng, Xiaoyan Ding, Jinglong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
hepatocellular carcinoma
transarterial chemoembolization
tyrosine kinase inhibitor
immune checkpoint inhibitor
propensity scores
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1533471/full
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