The transmembrane protein Syndecan is required for stem cell survival and maintenance of their nuclear properties.

Tissue maintenance is underpinned by resident stem cells whose activity is modulated by microenvironmental cues. Using Drosophila as a simple model to identify regulators of stem cell behaviour and survival in vivo, we have identified novel connections between the conserved transmembrane proteoglyca...

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Bibliographic Details
Main Authors: Buffy L Eldridge-Thomas, Jerome G Bohere, Chantal Roubinet, Alexandre Barthelemy, Tamsin J Samuels, Felipe Karam Teixeira, Golnar Kolahgar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011586
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