Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations.
House mice (Mus musculus) emit complex ultrasonic vocalizations (USVs) during social and sexual interactions, which have features similar to bird song (i.e., they are composed of several different types of syllables, uttered in succession over time to form a pattern of sequences). Manually processin...
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| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0181200&type=printable |
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| author | Sarah M Zala Doris Reitschmidt Anton Noll Peter Balazs Dustin J Penn |
| author_facet | Sarah M Zala Doris Reitschmidt Anton Noll Peter Balazs Dustin J Penn |
| author_sort | Sarah M Zala |
| collection | DOAJ |
| description | House mice (Mus musculus) emit complex ultrasonic vocalizations (USVs) during social and sexual interactions, which have features similar to bird song (i.e., they are composed of several different types of syllables, uttered in succession over time to form a pattern of sequences). Manually processing complex vocalization data is time-consuming and potentially subjective, and therefore, we developed an algorithm that automatically detects mouse ultrasonic vocalizations (Automatic Mouse Ultrasound Detector or A-MUD). A-MUD is a script that runs on STx acoustic software (S_TOOLS-STx version 4.2.2), which is free for scientific use. This algorithm improved the efficiency of processing USV files, as it was 4-12 times faster than manual segmentation, depending upon the size of the file. We evaluated A-MUD error rates using manually segmented sound files as a 'gold standard' reference, and compared them to a commercially available program. A-MUD had lower error rates than the commercial software, as it detected significantly more correct positives, and fewer false positives and false negatives. The errors generated by A-MUD were mainly false negatives, rather than false positives. This study is the first to systematically compare error rates for automatic ultrasonic vocalization detection methods, and A-MUD and subsequent versions will be made available for the scientific community. |
| format | Article |
| id | doaj-art-acbca6f1f23641f7b28c22f6aca3a9a7 |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-acbca6f1f23641f7b28c22f6aca3a9a72025-08-20T03:19:52ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01127e018120010.1371/journal.pone.0181200Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations.Sarah M ZalaDoris ReitschmidtAnton NollPeter BalazsDustin J PennHouse mice (Mus musculus) emit complex ultrasonic vocalizations (USVs) during social and sexual interactions, which have features similar to bird song (i.e., they are composed of several different types of syllables, uttered in succession over time to form a pattern of sequences). Manually processing complex vocalization data is time-consuming and potentially subjective, and therefore, we developed an algorithm that automatically detects mouse ultrasonic vocalizations (Automatic Mouse Ultrasound Detector or A-MUD). A-MUD is a script that runs on STx acoustic software (S_TOOLS-STx version 4.2.2), which is free for scientific use. This algorithm improved the efficiency of processing USV files, as it was 4-12 times faster than manual segmentation, depending upon the size of the file. We evaluated A-MUD error rates using manually segmented sound files as a 'gold standard' reference, and compared them to a commercially available program. A-MUD had lower error rates than the commercial software, as it detected significantly more correct positives, and fewer false positives and false negatives. The errors generated by A-MUD were mainly false negatives, rather than false positives. This study is the first to systematically compare error rates for automatic ultrasonic vocalization detection methods, and A-MUD and subsequent versions will be made available for the scientific community.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0181200&type=printable |
| spellingShingle | Sarah M Zala Doris Reitschmidt Anton Noll Peter Balazs Dustin J Penn Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. PLoS ONE |
| title | Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. |
| title_full | Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. |
| title_fullStr | Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. |
| title_full_unstemmed | Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. |
| title_short | Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. |
| title_sort | automatic mouse ultrasound detector a mud a new tool for processing rodent vocalizations |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0181200&type=printable |
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