Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients
Background: The term diabetes mellitus (DM) describes a group of chronic diseases and metabolic disorders that accompany hyperglycemia (high blood glucose) which may be the result of an abnormality in secretion or insulin action. Diabetes type 2 is the most common type of diabetes, it usually occurs...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-10-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | https://doi.org/10.4103/MJBL.MJBL_925_23 |
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| _version_ | 1841536813915701248 |
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| author | Sahar Salih Hussein Asal Aziz Tawfeeq |
| author_facet | Sahar Salih Hussein Asal Aziz Tawfeeq |
| author_sort | Sahar Salih Hussein |
| collection | DOAJ |
| description | Background: The term diabetes mellitus (DM) describes a group of chronic diseases and metabolic disorders that accompany hyperglycemia (high blood glucose) which may be the result of an abnormality in secretion or insulin action. Diabetes type 2 is the most common type of diabetes, it usually occurs in adults but is increasingly with overweight. On the other hand, gut bacteria have a key role in the regulation of different metabolic pathways that are important in glucose homeostasis and diabetes type 2 pathogenesis. Objectives: This study aimed to analyze the effect certain gut and biofilm formation on the glucose homeostasis and BMI in diabetic females. Materials and Methods: This study included the collection of 180 samples from diabetic and non-diabetic participants (20–50 years) during the period from December 2022 to March 2023. BMI was calculated for study participants, and Escherichia coli was microbiologically and biochemically identified. Results: The results demonstrated a substantial (P < 0.05) increase of 80% in biofilm formation E. coli in diabetic patients with greater BMI than those without diabetes with lower BMI. Conclusion: This study showed a significant relationship between intestinal bacteria (specially E. coli) and diabetes causing increased BMI, leading to probable useful tools for developing strategies to prevent obesity. |
| format | Article |
| id | doaj-art-acacdf34699e4c69ad0191f6120e0197 |
| institution | Kabale University |
| issn | 1812-156X 2312-6760 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj-art-acacdf34699e4c69ad0191f6120e01972025-01-14T11:24:47ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602024-10-0121Suppl 2S211S21610.4103/MJBL.MJBL_925_23Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic PatientsSahar Salih HusseinAsal Aziz TawfeeqBackground: The term diabetes mellitus (DM) describes a group of chronic diseases and metabolic disorders that accompany hyperglycemia (high blood glucose) which may be the result of an abnormality in secretion or insulin action. Diabetes type 2 is the most common type of diabetes, it usually occurs in adults but is increasingly with overweight. On the other hand, gut bacteria have a key role in the regulation of different metabolic pathways that are important in glucose homeostasis and diabetes type 2 pathogenesis. Objectives: This study aimed to analyze the effect certain gut and biofilm formation on the glucose homeostasis and BMI in diabetic females. Materials and Methods: This study included the collection of 180 samples from diabetic and non-diabetic participants (20–50 years) during the period from December 2022 to March 2023. BMI was calculated for study participants, and Escherichia coli was microbiologically and biochemically identified. Results: The results demonstrated a substantial (P < 0.05) increase of 80% in biofilm formation E. coli in diabetic patients with greater BMI than those without diabetes with lower BMI. Conclusion: This study showed a significant relationship between intestinal bacteria (specially E. coli) and diabetes causing increased BMI, leading to probable useful tools for developing strategies to prevent obesity.https://doi.org/10.4103/MJBL.MJBL_925_23biofilmbmidiabetesescherichia colikirkuk |
| spellingShingle | Sahar Salih Hussein Asal Aziz Tawfeeq Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients Medical Journal of Babylon biofilm bmi diabetes escherichia coli kirkuk |
| title | Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients |
| title_full | Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients |
| title_fullStr | Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients |
| title_full_unstemmed | Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients |
| title_short | Biofilm Forming Intestinal Escherichia coli as a Risk Factor for Increasing BMI in Type 2 Diabetic Patients |
| title_sort | biofilm forming intestinal escherichia coli as a risk factor for increasing bmi in type 2 diabetic patients |
| topic | biofilm bmi diabetes escherichia coli kirkuk |
| url | https://doi.org/10.4103/MJBL.MJBL_925_23 |
| work_keys_str_mv | AT saharsalihhussein biofilmformingintestinalescherichiacoliasariskfactorforincreasingbmiintype2diabeticpatients AT asalaziztawfeeq biofilmformingintestinalescherichiacoliasariskfactorforincreasingbmiintype2diabeticpatients |