Enucleated bone marrow-derived mesenchymal stromal cells regulate immune microenvironment and promote testosterone production through efferocytosis
Abstract Background Testosterone deficiency (TD) occurs most frequently in older men and can cause many health problems. Testosterone replacement therapy (TRT) is widely used to treat TD, but this regimen can lead to a series of side effects. Stem cell therapy has been wildly studied in vitro. Howev...
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Main Authors: | Lu Sun, Jiayu Huang, Xuezi Wang, Peng Huang, Baolin Dong, Zehang Liang, Jiahong Wu, Jiancheng Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Reproductive Biology and Endocrinology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12958-025-01352-9 |
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