The Transcriptional Regulator DhyR Positively Modulates Daptomycin Biosynthesis in Streptomyces roseosporus

ABSTRACT Daptomycin (DAP) is a cyclic lipopeptide antibiotic produced by Streptomyces roseosporus, and its biosynthesis is precisely regulated by a complex regulatory network. Although the biosynthetic pathway of DAP has been elucidated, the regulatory mechanism governing its biosynthesis at the tra...

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Bibliographic Details
Main Authors: Fuqiang He, Xinpeng Liu, Haiyi Wang, Xu Li, Yun Wu, Dan Zhang, Shufang Liang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Microbial Biotechnology
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Online Access:https://doi.org/10.1111/1751-7915.70110
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