Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix

Summary:. Giant congenital melanocytic nevi are large pigmented premalignant lesions present at birth that have an associated risk of malignant transformation. Full-thickness excision of these lesions would be required to eliminate this risk. However, giant nevi can leave behind large defects that c...

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Main Authors: Kareem W. Makkawi, MD, Paul T. Beaineh, MD, Saif E. Emsieh, MD, Edwin E. Chrabieh, BS, Amir E. Ibrahim, MD
Format: Article
Language:English
Published: Wolters Kluwer 2025-01-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006487
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author Kareem W. Makkawi, MD
Paul T. Beaineh, MD
Saif E. Emsieh, MD
Edwin E. Chrabieh, BS
Amir E. Ibrahim, MD
author_facet Kareem W. Makkawi, MD
Paul T. Beaineh, MD
Saif E. Emsieh, MD
Edwin E. Chrabieh, BS
Amir E. Ibrahim, MD
author_sort Kareem W. Makkawi, MD
collection DOAJ
description Summary:. Giant congenital melanocytic nevi are large pigmented premalignant lesions present at birth that have an associated risk of malignant transformation. Full-thickness excision of these lesions would be required to eliminate this risk. However, giant nevi can leave behind large defects that can be challenging to reconstruct. We present the case of a pediatric patient with a lesion occupying the entirety of the back, or around 18% total body surface area, and in whom Integra and meshed skin grafts were successfully used. This represents the largest defect size in the literature resulting from a giant nevus that has been treated by this method. Full take of the skin grafts was observed 26 days from the excision of the lesion with satisfactory functional outcomes.
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institution Kabale University
issn 2169-7574
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publishDate 2025-01-01
publisher Wolters Kluwer
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series Plastic and Reconstructive Surgery, Global Open
spelling doaj-art-ac93102565154052978df48403873ba32025-01-24T09:19:58ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-01-01131e648710.1097/GOX.0000000000006487202501000-00049Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute MatrixKareem W. Makkawi, MD0Paul T. Beaineh, MD1Saif E. Emsieh, MD2Edwin E. Chrabieh, BS3Amir E. Ibrahim, MD4From the * Division of Plastic and Reconstructive Surgery, Faculty of Medicine, American University of Beirut Medical Center, Beirut, LebanonFrom the * Division of Plastic and Reconstructive Surgery, Faculty of Medicine, American University of Beirut Medical Center, Beirut, LebanonFrom the * Division of Plastic and Reconstructive Surgery, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon† Faculty of Medicine, American University of Beirut, Beirut, Lebanon.From the * Division of Plastic and Reconstructive Surgery, Faculty of Medicine, American University of Beirut Medical Center, Beirut, LebanonSummary:. Giant congenital melanocytic nevi are large pigmented premalignant lesions present at birth that have an associated risk of malignant transformation. Full-thickness excision of these lesions would be required to eliminate this risk. However, giant nevi can leave behind large defects that can be challenging to reconstruct. We present the case of a pediatric patient with a lesion occupying the entirety of the back, or around 18% total body surface area, and in whom Integra and meshed skin grafts were successfully used. This represents the largest defect size in the literature resulting from a giant nevus that has been treated by this method. Full take of the skin grafts was observed 26 days from the excision of the lesion with satisfactory functional outcomes.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006487
spellingShingle Kareem W. Makkawi, MD
Paul T. Beaineh, MD
Saif E. Emsieh, MD
Edwin E. Chrabieh, BS
Amir E. Ibrahim, MD
Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix
Plastic and Reconstructive Surgery, Global Open
title Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix
title_full Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix
title_fullStr Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix
title_full_unstemmed Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix
title_short Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix
title_sort reconstruction of back defect from giant congenital melanocytic nevus using dermal substitute matrix
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006487
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