Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures
Abstract Hemorrhage is a leading cause of death in patients with severe pelvic fractures, and angiography and embolization (AE) is a crucial intervention for controlling arterial bleeding associated with these injuries. However, there is a paucity of data regarding the impact of the time from injury...
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Nature Portfolio
2025-04-01
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| Online Access: | https://doi.org/10.1038/s41598-025-88322-8 |
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| author | Bingze DuanMu Xuyang Du Jiaan Sun Tengjing Dong Hongya Guan Yanan Wu Hongkai Lian |
| author_facet | Bingze DuanMu Xuyang Du Jiaan Sun Tengjing Dong Hongya Guan Yanan Wu Hongkai Lian |
| author_sort | Bingze DuanMu |
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| description | Abstract Hemorrhage is a leading cause of death in patients with severe pelvic fractures, and angiography and embolization (AE) is a crucial intervention for controlling arterial bleeding associated with these injuries. However, there is a paucity of data regarding the impact of the time from injury to AE treatment (TIAE) on patient outcomes. This study investigates TIAE on outcomes in 161 patients with severe pelvic fractures, retrospectively analyzed from January 2019 to November 2024. Nonsurvivors exhibited a longer TIAE (19.9 ± 20.0 h) and higher Injury Severity Scores (ISSs) (39.4 ± 12.2) compared to survivors (11.1 ± 14.9 h and 28.4 ± 9.0, respectively). Age was not identified as a significant predictor of mortality (p = 0.795). Multivariate logistic regression confirmed ISS as an independent risk factor for mortality, while linear regression demonstrated a positive correlation between TIAE and both hospital and ICU stays, as well as transfusion volume. A significant reduction in the shock index was observed post-AE, particularly among patients receiving early AE, who also experienced lower mortality rates. This research underscores the importance of minimizing TIAE to enhance survival and improve clinical outcomes, highlighting the necessity for prompt AE in the emergency management of severe pelvic fractures. |
| format | Article |
| id | doaj-art-ac929edac24d4afa9d3ec879f185d97d |
| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-ac929edac24d4afa9d3ec879f185d97d2025-08-20T02:11:41ZengNature PortfolioScientific Reports2045-23222025-04-0115111010.1038/s41598-025-88322-8Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fracturesBingze DuanMu0Xuyang Du1Jiaan Sun2Tengjing Dong3Hongya Guan4Yanan Wu5Hongkai Lian6Institute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityResearch of Trauma Center, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityAbstract Hemorrhage is a leading cause of death in patients with severe pelvic fractures, and angiography and embolization (AE) is a crucial intervention for controlling arterial bleeding associated with these injuries. However, there is a paucity of data regarding the impact of the time from injury to AE treatment (TIAE) on patient outcomes. This study investigates TIAE on outcomes in 161 patients with severe pelvic fractures, retrospectively analyzed from January 2019 to November 2024. Nonsurvivors exhibited a longer TIAE (19.9 ± 20.0 h) and higher Injury Severity Scores (ISSs) (39.4 ± 12.2) compared to survivors (11.1 ± 14.9 h and 28.4 ± 9.0, respectively). Age was not identified as a significant predictor of mortality (p = 0.795). Multivariate logistic regression confirmed ISS as an independent risk factor for mortality, while linear regression demonstrated a positive correlation between TIAE and both hospital and ICU stays, as well as transfusion volume. A significant reduction in the shock index was observed post-AE, particularly among patients receiving early AE, who also experienced lower mortality rates. This research underscores the importance of minimizing TIAE to enhance survival and improve clinical outcomes, highlighting the necessity for prompt AE in the emergency management of severe pelvic fractures.https://doi.org/10.1038/s41598-025-88322-8Angiography and embolizationPelvic fracturesEmergency careClinical outcomesShock index |
| spellingShingle | Bingze DuanMu Xuyang Du Jiaan Sun Tengjing Dong Hongya Guan Yanan Wu Hongkai Lian Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures Scientific Reports Angiography and embolization Pelvic fractures Emergency care Clinical outcomes Shock index |
| title | Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures |
| title_full | Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures |
| title_fullStr | Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures |
| title_full_unstemmed | Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures |
| title_short | Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures |
| title_sort | timely angiography and embolization is effective emergency treatment for severe post traumatic pelvic fractures |
| topic | Angiography and embolization Pelvic fractures Emergency care Clinical outcomes Shock index |
| url | https://doi.org/10.1038/s41598-025-88322-8 |
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