The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial
Background: There is a positive relationship between aggressive behaviors and gut microbiota composition. The present study aimed to investigate the effect of synbiotic supplementation on self-reported aggression in healthy adult men. Methods: This double-blind randomized controlled clinical trial w...
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| Format: | Article |
| Language: | English |
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Shahid Sadoughi University of Medical Sciences and Health Services
2025-02-01
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| Series: | Journal of Nutrition and Food Security |
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| Online Access: | http://jnfs.ssu.ac.ir/article-1-986-en.pdf |
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| author | Rahele Sadat Montazeri Farzad Shidfar Fatemeh Sadat Hosseini-Baharanchi Golraste Kholasezadeh |
| author_facet | Rahele Sadat Montazeri Farzad Shidfar Fatemeh Sadat Hosseini-Baharanchi Golraste Kholasezadeh |
| author_sort | Rahele Sadat Montazeri |
| collection | DOAJ |
| description | Background: There is a positive relationship between aggressive behaviors and gut microbiota composition. The present study aimed to investigate the effect of synbiotic supplementation on self-reported aggression in healthy adult men. Methods: This double-blind randomized controlled clinical trial was conducted on 100 healthy adult men working at Iran University of Medical Sciences. Members of synbiotic group (SG) received 2 capsules daily containing 500 mg of synbiotic (Familact) and members of placebo group (PG) received 2 placebo capsules daily for 8 weeks. The intensity of aggression (verbal, physical aggression, hostility, and anger), depression, anxiety and stress, food intake, physical activity, and anthropometric indicators were measured at the beginning and end of the study. Statistical analysis of data was done using SPSS software version 26. P-value <0.05 was considered significant. Results: Thirty people completed the study. The synbiotic supplement caused a significant decrease in total aggression at the end of the intervention, compared to PG (P=0.04). Moreover, verbal aggression decreased in both groups compared to the beginning of the study, while it was significant in SG (P=0.005). There was no difference in the intensity of physical aggression, anger, and hostility after intervention. Conclusion: Synbiotics may be useful in reducing self-reported aggression in healthy adult men. |
| format | Article |
| id | doaj-art-ac878ddfe5304ac682da613381d6701e |
| institution | Kabale University |
| issn | 2476-7417 2476-7425 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Shahid Sadoughi University of Medical Sciences and Health Services |
| record_format | Article |
| series | Journal of Nutrition and Food Security |
| spelling | doaj-art-ac878ddfe5304ac682da613381d6701e2025-02-08T10:57:36ZengShahid Sadoughi University of Medical Sciences and Health ServicesJournal of Nutrition and Food Security2476-74172476-74252025-02-01101124133The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled TrialRahele Sadat Montazeri0Farzad Shidfar1Fatemeh Sadat Hosseini-Baharanchi2Golraste Kholasezadeh3 Student Research Committee, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Department of Psychiatry, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Background: There is a positive relationship between aggressive behaviors and gut microbiota composition. The present study aimed to investigate the effect of synbiotic supplementation on self-reported aggression in healthy adult men. Methods: This double-blind randomized controlled clinical trial was conducted on 100 healthy adult men working at Iran University of Medical Sciences. Members of synbiotic group (SG) received 2 capsules daily containing 500 mg of synbiotic (Familact) and members of placebo group (PG) received 2 placebo capsules daily for 8 weeks. The intensity of aggression (verbal, physical aggression, hostility, and anger), depression, anxiety and stress, food intake, physical activity, and anthropometric indicators were measured at the beginning and end of the study. Statistical analysis of data was done using SPSS software version 26. P-value <0.05 was considered significant. Results: Thirty people completed the study. The synbiotic supplement caused a significant decrease in total aggression at the end of the intervention, compared to PG (P=0.04). Moreover, verbal aggression decreased in both groups compared to the beginning of the study, while it was significant in SG (P=0.005). There was no difference in the intensity of physical aggression, anger, and hostility after intervention. Conclusion: Synbiotics may be useful in reducing self-reported aggression in healthy adult men.http://jnfs.ssu.ac.ir/article-1-986-en.pdfaggressionangersynbioticadult. |
| spellingShingle | Rahele Sadat Montazeri Farzad Shidfar Fatemeh Sadat Hosseini-Baharanchi Golraste Kholasezadeh The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial Journal of Nutrition and Food Security aggression anger synbiotic adult. |
| title | The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial |
| title_full | The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial |
| title_fullStr | The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial |
| title_full_unstemmed | The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial |
| title_short | The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial |
| title_sort | effect of synbiotic supplementation on self reported aggression in healthy adult men a randomized double blind placebo controlled trial |
| topic | aggression anger synbiotic adult. |
| url | http://jnfs.ssu.ac.ir/article-1-986-en.pdf |
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