Hop2-Mnd1 functions as a DNA sequence fidelity switch in Dmc1-mediated DNA recombination
Abstract Homologous recombination during meiosis is critical for chromosome segregation and also gives rise to genetic diversity. Genetic exchange between homologous chromosomes during meiosis is mediated by the recombinase Dmc1, which is capable of recombining DNA sequences with mismatches. The Hop...
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| Main Authors: | Jo-Ching Peng, Hao-Yen Chang, Yuting Liang Sun, Mara Prentiss, Hung-Wen Li, Peter Chi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53641-3 |
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