Changes of primary headache related white matter lesions in pediatric patients

We aimed to describe the long-term prognosis of white matter lesions detected on magnetic resonance imaging in children with primary headache. Children who were admitted with the complaint of headache and had nonspecific white matter lesions on magnetic resonance imaging were included in the study....

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Main Authors: Erhan Bayram, Uluç Yiş, Cem Paketçi, Derya Okur, İpek Polat, Handan Çakmakcı, Semra Hız, Banu Anlar
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2018-08-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/871
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author Erhan Bayram
Uluç Yiş
Cem Paketçi
Derya Okur
İpek Polat
Handan Çakmakcı
Semra Hız
Banu Anlar
author_facet Erhan Bayram
Uluç Yiş
Cem Paketçi
Derya Okur
İpek Polat
Handan Çakmakcı
Semra Hız
Banu Anlar
author_sort Erhan Bayram
collection DOAJ
description We aimed to describe the long-term prognosis of white matter lesions detected on magnetic resonance imaging in children with primary headache. Children who were admitted with the complaint of headache and had nonspecific white matter lesions on magnetic resonance imaging were included in the study. The clinical findings of the patients were reinvestigated using the same magnetic resonance imaging scanner and acquisition protocol after at least a two year period. Magnetic resonance imaging results of the patients were documented in detail. Findings of the baseline and follow-up studies were compared with each other by the same radiologist. Among the 11 patients, 8 ( 72.7%) were male and 3 (27.3%) were female. Mean age of patients at the time of second imaging was 12.9±2.3 years. Eight (72.7%) had migraine without aura, 1 (9.1%) had tension-type headache and 2 (18.2%) had migraine with aura. The mean clinical follow-up period of the patients was 4.31±1.31 years. All patients had low headache frequency on the last control visit when compared to the first clinical findings. The follow-up magnetic resonance imaging studies showed two newly developed white matter lesions in two patients who had migraine without aura and the white matter lesions disappeared in the patient who had tension-type headache, compared to the baseline neuroimaging. Findings of the baseline and long-term follow-up magnetic resonance imaging studies of the patients with primary headache showed no significant changes in terms of the location, size and laterality. Repeated neuro-imaging studies are not warranted in the absence of the progression in clinical findings.
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spelling doaj-art-ac76dd35a3054f3b9922b052f17ec98d2025-08-20T03:01:11ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212018-08-0160410.24953/turkjped.2018.04.004Changes of primary headache related white matter lesions in pediatric patientsErhan Bayram0Uluç Yiş1Cem Paketçi2Derya Okur3İpek Polat4Handan Çakmakcı5Semra Hız6Banu Anlar7Division of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Division of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Division of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Division of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Division of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Division of Pediatric Neurology, Department of Pediatrics, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Division of Pediatric Neurology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. We aimed to describe the long-term prognosis of white matter lesions detected on magnetic resonance imaging in children with primary headache. Children who were admitted with the complaint of headache and had nonspecific white matter lesions on magnetic resonance imaging were included in the study. The clinical findings of the patients were reinvestigated using the same magnetic resonance imaging scanner and acquisition protocol after at least a two year period. Magnetic resonance imaging results of the patients were documented in detail. Findings of the baseline and follow-up studies were compared with each other by the same radiologist. Among the 11 patients, 8 ( 72.7%) were male and 3 (27.3%) were female. Mean age of patients at the time of second imaging was 12.9±2.3 years. Eight (72.7%) had migraine without aura, 1 (9.1%) had tension-type headache and 2 (18.2%) had migraine with aura. The mean clinical follow-up period of the patients was 4.31±1.31 years. All patients had low headache frequency on the last control visit when compared to the first clinical findings. The follow-up magnetic resonance imaging studies showed two newly developed white matter lesions in two patients who had migraine without aura and the white matter lesions disappeared in the patient who had tension-type headache, compared to the baseline neuroimaging. Findings of the baseline and long-term follow-up magnetic resonance imaging studies of the patients with primary headache showed no significant changes in terms of the location, size and laterality. Repeated neuro-imaging studies are not warranted in the absence of the progression in clinical findings. https://turkjpediatr.org/article/view/871childrenheadachelongterm evaluationmagnetic resonance imagingwhite matter lesions
spellingShingle Erhan Bayram
Uluç Yiş
Cem Paketçi
Derya Okur
İpek Polat
Handan Çakmakcı
Semra Hız
Banu Anlar
Changes of primary headache related white matter lesions in pediatric patients
The Turkish Journal of Pediatrics
children
headache
longterm evaluation
magnetic resonance imaging
white matter lesions
title Changes of primary headache related white matter lesions in pediatric patients
title_full Changes of primary headache related white matter lesions in pediatric patients
title_fullStr Changes of primary headache related white matter lesions in pediatric patients
title_full_unstemmed Changes of primary headache related white matter lesions in pediatric patients
title_short Changes of primary headache related white matter lesions in pediatric patients
title_sort changes of primary headache related white matter lesions in pediatric patients
topic children
headache
longterm evaluation
magnetic resonance imaging
white matter lesions
url https://turkjpediatr.org/article/view/871
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AT deryaokur changesofprimaryheadacherelatedwhitematterlesionsinpediatricpatients
AT ipekpolat changesofprimaryheadacherelatedwhitematterlesionsinpediatricpatients
AT handancakmakcı changesofprimaryheadacherelatedwhitematterlesionsinpediatricpatients
AT semrahız changesofprimaryheadacherelatedwhitematterlesionsinpediatricpatients
AT banuanlar changesofprimaryheadacherelatedwhitematterlesionsinpediatricpatients