Rhesus macaques show increased resistance to repeated SHIV intrarectal exposure following a heterologous regimen of rVSV vector vaccine expressing HIV antigen

Rhesus macaques show increased resistance to repeated SHIV intrarectal exposure following a heterologous regimen of rVSV vector vaccine expressing HIV antigen

Despite the human immunodeficiency virus (HIV) pandemic continuing worldwide for 40 years, no vaccine to combat the disease has been licenced for use in at risk populations. Here, we describe a novel recombinant vesicular stomatitis virus (rVSV) vector vaccine expressing modified HIV envelope glycop...

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Bibliographic Details
Main Authors: Joseph Jelinski, Monika M. Kowatsch, Marc-Alexandre Lafrance, Alice Berger, Jannie Pedersen, Hiva Azizi, Yue Li, Florine Scholte, Alejandro Gomez, Natasha Hollett, Toby Le, Matthew Wade, Hugues Fausther-Bovendo, Marc-Antoine de La Vega, George Babuadze, Ara, Claude Lamarre, Trina Racine, Chil-Yong Kang, Xiao-Jian Yao, Galit Alter, Eric Arts, Keith R. Fowke, Gary P. Kobinger
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
HIV
immunodeficiency
vaccine
prophylaxis
NHP
T-cell
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2251595
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