The PI3K p110δ regulates expression of CD38 on regulatory T cells.

The PI3K p110δ regulates expression of CD38 on regulatory T cells.

The PI3K pathway has emerged as a key regulator of regulatory T cell (Treg) development and homeostasis and is required for full Treg-mediated suppression. To identify new genes involved in PI3K-dependent suppression, we compared the transcriptome of WT and p110δ(D910A) Tregs. Among the genes that w...

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Bibliographic Details
Main Authors: Daniel T Patton, Marcus D Wilson, Wendy C Rowan, Dalya R Soond, Klaus Okkenhaug
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017359&type=printable
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