Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer

Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer

Abstract Background: Heterogeneous circulating tumor cells (CTCs) have been implicated in the formation of new metastases. However, circulating cells expressing both tumor and immune cell proteins are often dismissed as insignificant findings in CTC studies. Methods: Two non-contemporaneous blood sa...

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Main Authors: Nikki Higa, Audrey Limb, Valerie Hennes, Andrés Rivera, Rafael Nevarez, Anand Kolatkar, Carol K. Tweed, Adam I. Riker, Young Lee, Lorraine Tafra, Jeremy G. Perkins, Craig D. Shriver, Peter Kuhn, James Hicks
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-01024-0
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