Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG
The purpose of this study was to determine the effect of administering a dose of gonadotropin (PG-600) in cows with persistent corpus luteum (PCL) which were treated with prostaglandin F2 α (PGF2α) and human chorionic gonadotropin (hCG). This study used 20, three-year-old cows diagnosed with PCL, ha...
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| Format: | Article |
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Universitas Airlangga
2024-08-01
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| Series: | Ovozoa: Journal of Animal Reproduction |
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| Online Access: | https://e-journal.unair.ac.id/OVZ/article/view/54708 |
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| author | Sofia Brenieta Brilianti Sri Mulyati Wurlina Wurlina Budi Utomo Oky Setyo Widodo |
| author_facet | Sofia Brenieta Brilianti Sri Mulyati Wurlina Wurlina Budi Utomo Oky Setyo Widodo |
| author_sort | Sofia Brenieta Brilianti |
| collection | DOAJ |
| description | The purpose of this study was to determine the effect of administering a dose of gonadotropin (PG-600) in cows with persistent corpus luteum (PCL) which were treated with prostaglandin F2 α (PGF2α) and human chorionic gonadotropin (hCG). This study used 20, three-year-old cows diagnosed with PCL, had recently given birth, and were not pregnant. Cows were randomly allocated into groups T0, T1, T2 and T3. Cows in all groups were injected with PGF2α (25 mg/cow). Simultaneously, cows in groups T1, T2 and T3 were also injected with PG-600 at doses of 100, 150 and 200 IU/cow respectively. PGF2α and PG-600 were injected when PCL was identified. After that, cows showing signs of estrus were injected with hCG (100 IU/cow) and artificially inseminated 12-18 hours after the appearance of signs of estrus. AI was conducted using frozen thawed semen. Sixty days following AI, a pregnancy examination was conducted using USG. Estrus was detected in all treated cows, while the pregnancy rates varied. Compared with other groups, the groups given 100 and 150 IU PG-600 produced higher pregnancy rates. It could be concluded that the combination of 25 mg PGF2α, 150 IU PG-600, and 100 IU hCG was the most effective treatment to produce high pregnancy rates in cows with persistent corpus luteum. |
| format | Article |
| id | doaj-art-ac353e8df00d458989f0c82b58a4e7be |
| institution | OA Journals |
| issn | 2302-6464 2722-967X |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Ovozoa: Journal of Animal Reproduction |
| spelling | doaj-art-ac353e8df00d458989f0c82b58a4e7be2025-08-20T02:10:34ZengUniversitas AirlanggaOvozoa: Journal of Animal Reproduction2302-64642722-967X2024-08-01132909510.20473/ovz.v13i2.2024.90-9552870Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCGSofia Brenieta Brilianti0https://orcid.org/0009-0000-9694-2788Sri Mulyati1https://orcid.org/0000-0002-0193-4898Wurlina Wurlina2https://orcid.org/0000-0002-1307-3845Budi Utomo3https://orcid.org/0000-0002-1147-3263Oky Setyo Widodo4https://orcid.org/0000-0002-0073-1394Large Animal Veterinary Professional Interest Group Jalan Ir. Soekarno, Surabaya, IndonesiaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, IndonesiaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, IndonesiaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, IndonesiaLaboratory of Theriogenology. Joint Graduate School of Veterinary Medicine, Yamaguchi University, Yamaguchi, JapanThe purpose of this study was to determine the effect of administering a dose of gonadotropin (PG-600) in cows with persistent corpus luteum (PCL) which were treated with prostaglandin F2 α (PGF2α) and human chorionic gonadotropin (hCG). This study used 20, three-year-old cows diagnosed with PCL, had recently given birth, and were not pregnant. Cows were randomly allocated into groups T0, T1, T2 and T3. Cows in all groups were injected with PGF2α (25 mg/cow). Simultaneously, cows in groups T1, T2 and T3 were also injected with PG-600 at doses of 100, 150 and 200 IU/cow respectively. PGF2α and PG-600 were injected when PCL was identified. After that, cows showing signs of estrus were injected with hCG (100 IU/cow) and artificially inseminated 12-18 hours after the appearance of signs of estrus. AI was conducted using frozen thawed semen. Sixty days following AI, a pregnancy examination was conducted using USG. Estrus was detected in all treated cows, while the pregnancy rates varied. Compared with other groups, the groups given 100 and 150 IU PG-600 produced higher pregnancy rates. It could be concluded that the combination of 25 mg PGF2α, 150 IU PG-600, and 100 IU hCG was the most effective treatment to produce high pregnancy rates in cows with persistent corpus luteum.https://e-journal.unair.ac.id/OVZ/article/view/54708conception ratelimousin cowspregnant mare serum gonadotropinreproductive disorderultrasonography |
| spellingShingle | Sofia Brenieta Brilianti Sri Mulyati Wurlina Wurlina Budi Utomo Oky Setyo Widodo Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG Ovozoa: Journal of Animal Reproduction conception rate limousin cows pregnant mare serum gonadotropin reproductive disorder ultrasonography |
| title | Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG |
| title_full | Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG |
| title_fullStr | Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG |
| title_full_unstemmed | Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG |
| title_short | Effect of PG-600 dose in cows with persistent corpus luteum treated with PGF2α and hCG |
| title_sort | effect of pg 600 dose in cows with persistent corpus luteum treated with pgf2α and hcg |
| topic | conception rate limousin cows pregnant mare serum gonadotropin reproductive disorder ultrasonography |
| url | https://e-journal.unair.ac.id/OVZ/article/view/54708 |
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