Role of Vitamin E in Ischaemic Skin Flap Survival in Rats
The efficacy of free radical scavenger – Vitamin E (VE) in salvage of ischaemic skin flaps was studied in an experimental rat skin flap model. The animals were divided into two groups – a control group (N=15) who did of receive VE and a test group (N=15) who received VE starting one week preoperativ...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
1995-04-01
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| Series: | Indian Journal of Plastic Surgery |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1775701 |
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| Summary: | The efficacy of free radical scavenger – Vitamin E (VE) in salvage of ischaemic skin flaps was studied in an experimental rat skin flap model. The animals were divided into two groups – a control group (N=15) who did of receive VE and a test group (N=15) who received VE starting one week preoperatively. No significant difference was found in flap necrosis between the control group (38.365% ± 1.398% SEM) and the test group (35.288% ± 0.635% SEM), which received therapeutic dose of VE (100 mg/kg/day. 1 mg = 1.49 I.U). Further research is needed to establish the role of vitamin E as an agent of ischaemic skin flap salvage. |
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| ISSN: | 0970-0358 1998-376X |