Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin

A novel cyclic amylopectin (CA) was synthesized from waxy corn starch (WCS) using <i>Bacillus stearothermophilus</i> branching enzyme (BstBE), providing insights into its biosynthesis mechanism and solution properties. During the first 4 h, BstBE partially cyclized WCS, producing 68.20%...

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Main Authors: Ruolan Li, Yaning Shi, Ming Miao
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/13/21/3474
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author Ruolan Li
Yaning Shi
Ming Miao
author_facet Ruolan Li
Yaning Shi
Ming Miao
author_sort Ruolan Li
collection DOAJ
description A novel cyclic amylopectin (CA) was synthesized from waxy corn starch (WCS) using <i>Bacillus stearothermophilus</i> branching enzyme (BstBE), providing insights into its biosynthesis mechanism and solution properties. During the first 4 h, BstBE partially cyclized WCS, producing 68.20% CA with a significantly reduced molecular weight (M<sub>W</sub>), from 8.98 × 10⁶ to 3.19 × 10⁴ g/mol and a lower polymer dispersity index (PDI), decreasing from 1.97 to 1.12. This resulted in a uniform CA structure with shorter chain lengths, particularly increasing DP 3–13, especially DP 7–9. Over the subsequent 4–12 h, the PDI slightly increased to 1.18 as the CA content decreased to 50.48%, with an increase in small ring structures (DP 6–12) of CA, suggesting both ring-opening and ring-downsizing due to continued enzyme catalysis. These results propose a two-stage reaction model: initial cyclization followed bybranching and secondary cyclization. CA exhibited excellent solution properties, with BE-4 and BE-12 samples demonstrating high solubility (≥65 g/100 mL), low viscosity (<0.01 Pa·s), and over 90% light transmittance after 14 days at 4 °C, highlighting its broad application potential.
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spelling doaj-art-ac1c4e6fd89f4c3695382a347fa47cdf2025-08-20T02:13:14ZengMDPI AGFoods2304-81582024-10-011321347410.3390/foods13213474Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic AmylopectinRuolan Li0Yaning Shi1Ming Miao2State Key Laboratory of Food Science & Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaState Key Laboratory of Food Science & Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, ChinaA novel cyclic amylopectin (CA) was synthesized from waxy corn starch (WCS) using <i>Bacillus stearothermophilus</i> branching enzyme (BstBE), providing insights into its biosynthesis mechanism and solution properties. During the first 4 h, BstBE partially cyclized WCS, producing 68.20% CA with a significantly reduced molecular weight (M<sub>W</sub>), from 8.98 × 10⁶ to 3.19 × 10⁴ g/mol and a lower polymer dispersity index (PDI), decreasing from 1.97 to 1.12. This resulted in a uniform CA structure with shorter chain lengths, particularly increasing DP 3–13, especially DP 7–9. Over the subsequent 4–12 h, the PDI slightly increased to 1.18 as the CA content decreased to 50.48%, with an increase in small ring structures (DP 6–12) of CA, suggesting both ring-opening and ring-downsizing due to continued enzyme catalysis. These results propose a two-stage reaction model: initial cyclization followed bybranching and secondary cyclization. CA exhibited excellent solution properties, with BE-4 and BE-12 samples demonstrating high solubility (≥65 g/100 mL), low viscosity (<0.01 Pa·s), and over 90% light transmittance after 14 days at 4 °C, highlighting its broad application potential.https://www.mdpi.com/2304-8158/13/21/3474starchbranching enzymecyclic amylopectinbiosynthesissolution properties
spellingShingle Ruolan Li
Yaning Shi
Ming Miao
Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin
Foods
starch
branching enzyme
cyclic amylopectin
biosynthesis
solution properties
title Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin
title_full Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin
title_fullStr Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin
title_full_unstemmed Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin
title_short Deciphering Biosynthesis Mechanism and Solution Properties of Cyclic Amylopectin
title_sort deciphering biosynthesis mechanism and solution properties of cyclic amylopectin
topic starch
branching enzyme
cyclic amylopectin
biosynthesis
solution properties
url https://www.mdpi.com/2304-8158/13/21/3474
work_keys_str_mv AT ruolanli decipheringbiosynthesismechanismandsolutionpropertiesofcyclicamylopectin
AT yaningshi decipheringbiosynthesismechanismandsolutionpropertiesofcyclicamylopectin
AT mingmiao decipheringbiosynthesismechanismandsolutionpropertiesofcyclicamylopectin