A Near-Infrared Fluorescent Probe for Specific Imaging of Lymph Node Metastases in Ovarian Cancer via Active Targeting of the Gonadotropin-Releasing Hormone Receptor

A Near-Infrared Fluorescent Probe for Specific Imaging of Lymph Node Metastases in Ovarian Cancer via Active Targeting of the Gonadotropin-Releasing Hormone Receptor

Lymph node metastases are common in advanced ovarian cancer and are associated with poor prognosis. Accurate intraoperative identification of lymph node metastases remains a challenge in ovarian cancer surgery due to the lack of tumor-specific intraoperative imaging tools. Here, we developed a gonad...

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Bibliographic Details
Main Authors: Qiyu Liu, Jiaan Sun, Xiaobo Zhou, Mingxing Zhang, Tao Pu, Xiaolan Gao, Meng Zhang, Congjian Xu, Xiaoyan Zhang
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
intraoperative imaging agents
tumor targeting
ovarian cancer
gonadotropin-releasing hormone
lymph node metastasis
Online Access:https://www.mdpi.com/2218-273X/15/6/868
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